Results 131 to 140 of about 197,897 (274)

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

GAN-based Virtual Re-Staining: A Promising Solution for Whole Slide Image Analysis

, 2019
Histopathological cancer diagnosis is based on visual examination of stained tissue slides. Hematoxylin and eosin (H\&E) is a standard stain routinely employed worldwide.
Bozóky, Béla, Moro, Carlos Fernández, Xu, Zhaoyang, Zhang, Qianni   +3 more
core  

Copolymers of Poly(Butylene Trans‐1,4‐Cyclohexanedicarboxylate)/Pripol as New Biomaterial Platform for Small Diameter Vascular Graft

Advanced Healthcare Materials, EarlyView.
Electrospun tubular scaffolds from novel PBCE‐based copolyesters and blends were designed as candidates for small‐diameter vascular grafts. They combine defect‐free architecture, blood‐compatible surfaces, and mechanical properties comparable to native vessels.
Edoardo Bondi, Gabriele Obino, Giulia Guidotti, Alberto Sensini, Martijn van Griensven, Antonio Junior Lepedda, Nadia Lotti, Lorenzo Moroni   +7 more
wiley   +1 more source

PolyGraph – Flexible, Biocompatible & Electrically Optimized Graphene‐Polymer Composites for Next‐Generation Neural Interfaces

Advanced Healthcare Materials, EarlyView.
PolyGraph, a flexible graphene‐polycaprolactone nanocomposite, unites conductivity, biocompatibility, and processability for next‐generation neural interfaces. Fabricated into microneedle arrays with ultra‐flexible backings, PolyGraph enables bidirectional neuronal recording and stimulation in brain tissue, advancing brain‐computer interface (BCI) and ...
Jack Maughan, Ian Woods, Cian O'Connor, Pablo Quintana‐Sarti, Eoin Caffrey, Jose M. Munuera, Tian Carey, Adrian Dervan, Alejandro López Valdés, Omar Mamad, Maeve A. Caldwell, Fergal J. O'Brien, Jonathan N. Coleman   +12 more
wiley   +1 more source

Digital Whole Slide Imaging in Cytology

Archives of Pathology and Laboratory Medicine, 2014
Ioan C, Cucoranu, Anil V, Parwani, Liron, Pantanowitz   +2 more
openaire   +2 more sources

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Whole-Slide Imaging, Mutual Information Registration for Multiplex Immunohistochemistry and Immunofluorescence. [PDF]

Lab Invest, 2023
Doyle J, Green BF, Eminizer M, Jimenez-Sanchez D, Lu S, Engle EL, Xu H, Ogurtsova A, Lai J, Soto-Diaz S, Roskes JS, Deutsch JS, Taube JM, Sunshine JC, Szalay AS.   +14 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Colour reproduction evaluation of whole-slide imaging scanners for digital pathology

Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization
Digital pathology using whole-slide imaging (WSI) scanners aids pathologists challenged by diagnostic volume and novel diagnostic methods. Colour reproducibility of WSI scanners is crucial for accurate digital diagnoses.
Akihiro Kubota, Motohiro Shibata, Susumu Kikuchi, Takashi Yoneyama   +3 more
doaj   +1 more source