Results 41 to 50 of about 5,116 (237)
Modifying Wicking Speeds in Paper-Based Microfluidic Devices by Laser-Etching
Micromachines, 2020 Paper-based microfluidic devices are an attractive platform for developing low-cost, point-of-care diagnostic tools. As paper-based devices’ detection chemistries become more complex, more complicated devices are required, often entailing the sequential ...
Brent Kalish +2 more
doaj +1 more source
BMJ Open, 2023 Introduction Evidence suggests that the pathology underlying cognitive decline leading to dementia begins 15–20 years before cognitive symptoms emerge. Thus, identifying biomarkers in this preclinical phase is critically important.
Jane Alty +3 more
doaj +1 more source
Wicked problems or wicked people? Reconceptualising institutional abuse [PDF]
Sociology of Health & Illness, 2012 AbstractInstitutional abuse is a global issue, sometimes ascribed to the behaviour of a few wicked people. It persists despite regulatory measures, interventions from enforcement and protection agencies, organisational policies and procedures. Therefore, the accurate recognition and early detection of abuse and taking corresponding steps to deal with ...
Burns, Diane +2 more
openaire +5 more sources
A Perspective on Interactive Theorem Provers in Physics
Advanced Science, EarlyView.Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley +1 more source
Frontiers in Aging NeuroscienceIntroductionPrevious research has tended to focus on early-life education for dementia risk reduction, yet there are great gains for building cognitive reserve in mid- to later-life through educational interventions.
Eddy Roccati +10 more
doaj +1 more source
TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
Disease Models & Mechanisms, 2021 Mislocalization of the TAR DNA-binding protein 43 (TDP-43; encoded by TARDBP) from the nucleus to the cytoplasm is a common feature of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD ...
Rachel Atkinson +5 more
doaj +1 more source
Thermally Induced Creep and Viscoelastic Behavior of Copper Micropillar Arrays
Advanced Science, EarlyView.Copper micropillar arrays are fabricated by electrodeposition within through‐glass‐via, and their thermally induced time‐dependent deformation is quantified. Nanoindentation creep, EBSD, and TEM reveal a heat‐treatment‐driven transition between grain‐boundary‐mediated deformation and dislocation‐dominated creep, while Kelvin modeling captures ...
Miao Wang +14 more
wiley +1 more source
Wicked Solutions for Wicked Problems
Journal of Systems Thinking“Wicked problems” are often thought of as a situation that should not exist or an inescapable consequence of complex systems. This paper argues for a paradigm shift in instead understanding wicked problems as feedback from the system (i.e., the real world), resulting from a misalignment between our mental model of the system and the system itself ...
Natasha Steinhall +7 more
openaire +1 more source
Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics
Advanced Science, EarlyView.Deformation‐driven suction cups enable robust, reversible adhesion of wearable electronics to human skin spanning wide mechanical compliance, without adhesives or tight straps. By integrating mechanics modeling, experiments, and contact mechanics theory, this work reveals how cup geometry, substrate compliance, and interfacial adhesion govern suction ...
Seola Lee +10 more
wiley +1 more source
Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases
Advanced Science, EarlyView.Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao +5 more
wiley +1 more source