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Quality Assessment of Shuxuening Injection Based on Widely Targeted Metabolomics Approach
Journal of Pharmaceutical and Biomedical Analysis, 2020Shuxuening injection (SXNI) is the pharmaceutical preparations of Ginkgo biloba for treating coronary heart disease, stenocardia and ischemic cerebrovascular disease. In order to guarantee the clinical efficacy and drug safety, the chemical and biological variation of SXNIs from different manufacturers should be monitored and controlled. In this study,
Xuemei Qin, Shuting Yu
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Development of a widely-targeted metabolomics method based on gas chromatography-mass spectrometry
Chinese Journal of Chromatography, 2023Gas chromatography-mass spectrometry (GC-MS) detectors are widely used detection instruments owing to their distinct advantages over other analytical techniques, including lower sample consumption, higher sensitivity, faster analysis speed, and simultaneous separation and analysis.
Ya-Ting, Wang +3 more
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Identification of key taste components in loquat using widely targeted metabolomics
Food Chemistry, 2020Loquats can be divided into white- and yellow-fleshed cultivars. Generally, white-fleshed cultivars taste better than yellow-fleshed cultivars. Currently, metabolic causes of differences in taste are unknown, due to the lack of a large-scale and comprehensive investigation of metabolites in loquat fruit.
Shicheng Zou +6 more
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Distinct Quality Changes of Asparagus during Growth by Widely Targeted Metabolomics Analysis
Journal of Agricultural and Food Chemistry, 2022Asparagus is a popular vegetable and traditional medicine consumed worldwide due to its health benefits. The quality of asparagus, mainly attributed to small components like flavonoids and steroid, is quite differential as a result of different environments and maturities.
Pingxiang Liu +6 more
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Development of a
AbstractThe objective of this work was the development of a detailed, extensive and reliable database of the metabolomes of P. vittata. Using an ultra‐performance liquid chromatography–triple quadrupole tandem mass spectrometry system (UPLC‐QqQ‐MS/MS) and based on the knowledge of retention time and mass spectral characteristics of an in‐house ...
Nguyen, Thi Kieu Oanh +6 more
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Molecules, 2018 Chemical composition of secondary metabolites is of great importance for quality control of agricultural products. Black sesame seeds are significantly more expensive than white sesame seeds, because it is thought that black sesame seeds are more ...
Jin Mao, Xiupin Wang, Peiwu Li
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Wide spectrum targeted metabolomics identifies potential ovarian cancer biomarkers
Life Sciences, 2019Despite of almost a hundred years of research on cancer metabolism, the biological background of cancerogenesis and cancer-related reprogramming of metabolism remains not fully understood. In order to comprehensively and effectively diagnose and treat the deadliest diseases, the mechanisms underlying these diseases have to be discovered urgently. Among
Szymon Plewa +5 more
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Food Chemistry, 2022
Microbial fermentation can break the bee pollen wall. However, the global profiling of bee pollen metabolites under fermentation remains unclear. This study aims to comprehensively elucidate the changes in the composition of bee pollen after microbial fermentation.
Huifang, Zhang, Qun, Lu, Rui, Liu
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Microbial fermentation can break the bee pollen wall. However, the global profiling of bee pollen metabolites under fermentation remains unclear. This study aims to comprehensively elucidate the changes in the composition of bee pollen after microbial fermentation.
Huifang, Zhang, Qun, Lu, Rui, Liu
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Widely targeted metabolomics analysis flavonoid metabolites in different purple teas
Food ChemistryPurple teas are gaining popularity due to their significant health benefits. This study analyzed flavonoid metabolites in the second leaves of three purple tea varieties with stable purple shoots-'Hongfei' (HF), 'Danfei' (DF), and 'Ziya 24' (ZY24)-using UPLC-MS/MS, with 'Yinghong 9' (YH9), a green tea, as the control.
Qing, Wang +8 more
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Analytica Chimica Acta, 2019
Either widely targeted metabolomics or quantitative proteomics usually requires unique analytical platform. However, cross-platform omics studies entail higher levels of complexity and uncertainty, and result in a significant obstacle for high throughput assay as well.
Wenjing Liu +8 more
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Either widely targeted metabolomics or quantitative proteomics usually requires unique analytical platform. However, cross-platform omics studies entail higher levels of complexity and uncertainty, and result in a significant obstacle for high throughput assay as well.
Wenjing Liu +8 more
openaire +2 more sources