Results 101 to 110 of about 2,533,574 (314)
3D microCT reconstruction of mouse tibiae-wild ...
Anna Maria Ranzoni (4067443) +3 more
core +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Wild Discovery Guide: Shark Bay - Ningaloo Coast and Outback Pathways, Western Australia
The Shark Bay-Ningaloo Coast extends 600km from north to south and the Outback Pathways cover more than 3,000km of Outback roads, all exhibiting a stunning diversity of organisms and geological and human history. Habitats include oceanic, bay, sea floor,
Zell, Leonard Douglas, Bedford, Susan
core
3D microCT reconstruction of mouse tibiae-wild ...
Anna Maria Ranzoni (4067443) +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
3D microCT reconstruction of mouse tibiae-wild ...
Anna Maria Ranzoni (4067443) +3 more
core +1 more source
This article proposes a critical discourse around the notions of sustainability, beauty, and togetherness in the field of design thinking by placing them in a field defined by terms such as discomfort, queer and wild.
Camillo Boano, Antonio di Campli
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
3D microCT reconstruction of mouse tibiae-wild ...
Anna Maria Ranzoni (4067443) +3 more
core +1 more source
The paper distinguishes between two kinds of knowledge, productive or armed knowledge and connective or tribal knowledge, which it traces back to pre-modern antagonisms. It argues that open knowledge depends on a new ‘agonistic’ synthesis of these types.
Hartley John
doaj +1 more source

