Results 71 to 80 of about 4,374,159 (298)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Distribution and germination of wild and cultivated Ensete ventricosum in Ethiopia

open access: yesInternational Journal of Science, Technology, Engineering and Mathematics
Enset (Ensete ventricosum (Welw.) Cheesman) is a traditional staple crop that is economically significant for over 20 million people in the central, southern and southwestern regions of Ethiopia.
Melese Bekele Hemade
doaj   +1 more source

Shortcomings of learning design approaches and a possible way out [PDF]

open access: yes, 2008
Shifting away from traditional instructional design to younger research streams like personalized, workflow-based or collaborative e-learning, learning design (LD) has become an important issue in the field of technology-enhanced learning.
Moedritscher, Felix, Wild, Fridolin
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Poetry at Home:Discrepancies of an anthropo-cosmic space / Evdeki Şiir: Antropo-Kozmik Bir Mekânın Çelişki [PDF]

open access: yesFolklor/Edebiyat, 2016
In this article, the book ‘Home Time’ by one of contemporary Turkish poets, Abdulkadir Budak, through the contained poem ‘Home, Pain’ on focus is examined.
Aydın Afacan*
doaj  

K-band Imaging of strong CaII-absorber host galaxies at z~1

open access: yes, 2007
We present K-band imaging of fields around 30 strong CaII absorption line systems, at 0 ...
Hewett, Paul, Wild, Vivienne
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Construction géohistorique du « sauvage » de la Garonne toulousaine : quelle part de naturalité dans les paysages fluviaux ? (3ème partie)

open access: yesDéveloppement Durable et Territoires, 2014
The Garonne between Toulouse and the confluence of the Tarn is composed of many wetlands. Here, various protective devices would label a "wild" dimension to the river, supporting its maintenance and conservation without actually questioning their ...
Philippe Valette   +4 more
doaj   +1 more source

Realization of abstract convex geometries by point configurations, Part 1 [PDF]

open access: yes, 2007
The Edelman-Jamison problem is to characterize those abstract convex geometries that are representable by a set of points in the plane. We show that some natural modification of the Edelman-Jamison problem is equivalent to the well known NP-hard order ...
Adaricheva, Kira, Wild, Marcel
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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