Results 71 to 80 of about 6,489,977 (312)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
An Integrated Study of Ramie (Boehmeria nivea), and Its Wild, Cultivated, and Feral Forms
Ecology and EvolutionFeralization, the re‐establishment of wild populations from domesticated ancestors, can involve multiple parallel character reversions and potentially also rampant gene flow with cultivated and/or naturally wild material.
Ying Zhao +7 more
doaj +1 more source
Scientific Data, 2023 Nervonic acid (C24:1 Δ15, NA) is a very long-chain monounsaturated fatty acid, a clinically indispensable resource in maintaining the brain and nerve cells development and regeneration.
Tianquan Yang +10 more
doaj +1 more source
Foods, 2019 Wild plants may play an important role in human nutrition and health and, among them, many are the leafy species. We hypothesized that the wild greens could be profitably grown as microgreens and baby greens, specialty products whose market is increasing.
A. Lenzi +4 more
semanticscholar +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Pulsed evolution shaped extant angiosperm pollen disparity
Nature CommunicationsPollen grains, the male gametophyte of seed plants, are enclosed within sporopollenin walls that yield remarkable structural diversity and exceptional preservation, making them invaluable proxies for past plant diversity.
Yang Luo +15 more
doaj +1 more source
Coronaviruses in Avian Species – Review with Focus on Epidemiology and Diagnosis in Wild Birds
Journal of Veterinary Research, 2018 Coronaviruses (CoVs) are a large group of enveloped viruses with a single-strand RNA genome, which continuously circulate in mammals and birds and pose a threat to livestock, companion animals, and humans.
J. Miłek, Katarzyna Blicharz-Domańska
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
, 2015 Along history, wild plants have been introduced into cultivation and domestic derivatives radically altered by this move due to changes in selection pressure: wild species are exposed to natural selection that operates to continue survival and ...
A. Vilela, L. González-Paleo
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source