Results 101 to 110 of about 34,166 (314)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Correspondence from Utah Wilderness Association to Desmond Anderson, February 2, 1989
, 1989 Correspondence from Utah Wilderness Association to Desmond Anderson explaining the benefits of membership with the Utah Wilderness Association.
Carter, Dick;
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Governance challenges for wildland preservation in Canada and Mexico [PDF]
, 2018 The proposed Castle Wilderness (Canada) and the Monarch Butterfly Biosphere Reserve (Mexico) are used to demonstrate the application of a pluridimensional spectrum of governance framework to evaluate the influence of governance on the establishment and ...
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Episode 1 : Communities of the Selway-Bitterroot Wilderness, part 1: an interview with Sarah Walker
, 2010 Interview with Sarah Walker | Moscow, Idaho | December 15, 2010 |Interviewed by Debbie Lee and Jane Holman, Moscow, Idaho. In this episode, titled ""Communities of the Selway-Bitterroot Wilderness, part 1,"" we hear reminiscences from Sarah Walker who
Debbie Lee; Jane Holman; Sarah Walker;
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Free-Flowing Waters: A Vision for a Lower Mississippi River Wilderness
Open Rivers, 2018 Wilderness is a feeling. It is more than that, of course—wilderness is the wind and the water, the turtles and coyotes, all that exists beyond and around and within our human selves.
John Ruskey and Boyce Upholt
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Episode 3 : Legends of the Selway-Bitterroot Wilderness: an interview with Jean Carroll
, 2011 Interview with: Jean (Renshaw) Carroll | Interviewers: Debbie Lee, Jane Holman | Location: Red Fir Road, Kooskia, Idaho | Date: February 8, 2011.
Debbie Lee; Jane Holman; Jean Carroll;
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source