Results 191 to 200 of about 5,194,122 (262)

Heterogeneous effects of donor‐related risk factors in 954 pediatric liver transplantations

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Accepting a suitable donor for a child awaiting pediatric liver transplantation (pLT) is increasingly challenging. Donor‐specific risk factors influence post‐transplant outcomes, but evidence in pediatric patients remains inconsistent.
Christoph Leiskau, Norman Junge, Tobias Laue, Imeke Goldschmidt, Frauke E. Mutschler, Moritz Schmelzle, Nicolas Richter, Philipp Felgendreff, Cornelius J. van Beekum, Florian W. R. Vondran, Clara A. Weigle, Eva‐D. Pfister, Ulrich Baumann   +12 more
wiley   +1 more source

Role and mechanisms of cuproptosis in the pathogenesis of Wilson's disease (Review). [PDF]

Int J Mol Med
Chen H, Wang X, Xing J, Pu Y, Ye H, Ma Y, Zhang J.   +6 more
europepmc   +1 more source

Fecal microRNA signatures as non‐invasive diagnostic and prognostic markers of pediatric inflammatory bowel diseases

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The identification of novel noninvasive diagnostic and prognostic biomarkers for pediatric inflammatory bowel disease (PIBD), including pediatric Crohn's disease (pCD) and ulcerative colitis (pUC), is crucial for improving therapeutic outcomes.
Tereza Pinkasova, Tereza Deissova, Matej Hrunka, Martina Ambrozova, Dagmar Al Tukmachi, Robin Jugas, Lenka Radova, Julia Bohosova, Tana Machackova, Leos Kren, Ondrej Slaby, Petr Jabandziev   +11 more
wiley   +1 more source

Prebiotic Effects of <i>Lycium barbarum</i> Polysaccharides on Gut Microbiota and Short-Chain Fatty Acids Production in Wilson's Disease: An In Vitro Fermentation Study. [PDF]

Food Sci Nutr
Fang S, Zhang K, Fang X, Liu D, Yang Y, Chen G, Yang W.   +6 more
europepmc   +1 more source

Impact of cystic fibrosis transmembrane conductance regulator modulator therapies on liver stiffness and liver enzymes: An observational perspective single‐center cohort study

JPGN Reports, EarlyView.
Abstract Objectives The efficacy of cystic fibrosis transmembrane conductance regulator (CFTR)‐modulator therapies in preventing or ameliorating cystic fibrosis liver disease (CFLD) by correcting CFTR in cholangiocytes is not well‐documented. This study aimed to assess liver function during CFTR‐modulators.
Laura Giugliano, Elisabetta Augustoni, Antonio Pizzol, Anna Opramolla, Cristina Chiadò, Anna Zagaria, Irene Esposito, Giulia Roberto, Alice Ponte, Andrea Evangelista, Paola Quarello, Michele Pinon, Pier Luigi Calvo   +12 more
wiley   +1 more source

Attenuated dietary motivation in Wilson's disease correlates with clinical severity. [PDF]

Orphanet J Rare Dis
Wang XQ, Wang YX, Ye ZH, Zhang ZL, Pan X, Wang XC, Cen SF.   +6 more
europepmc   +1 more source

Delayed diagnosis of hereditary fructose intolerance presenting as chronic lean steatosis in an adolescent

JPGN Reports, EarlyView.
Abstract Hereditary fructose intolerance (HFI) typically presents in infancy with acute metabolic crisis upon the introduction of fructose. We report a case of a 13‐year‐old female with chronic abdominal pain, short stature, and persistent mild transaminitis.
Alexandra Hurlock, Melissa Lah, Hannah Sue Hyaduck, Jean P. Molleston, Chaowapong Jarasvaraparn   +4 more
wiley   +1 more source

Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease. [PDF]

Ann Clin Transl Neurol
Fan SP, Chen YF, Li CH, Kuo YC, Lee NC, Chien YH, Hwu WL, Tseng TC, Su TH, Hsu CT, Chen HL, Lin CH, Ni YH.   +12 more
europepmc   +1 more source

Biochemical testing and pathology reveal rare cause of pediatric acute liver failure: Hyperornithinemia‐hyperammonemia‐homocitrullinuria syndrome

JPGN Reports, EarlyView.
Abstract Hyperornithinemia‐hyperammonemia‐homocitrullinuria (HHH) syndrome is a rare metabolic condition that can cause lethargy, ataxia, tachypnea, nausea, vomiting, seizures, coma, and acute liver failure. We present a 26‐month‐old female with acute liver failure who was diagnosed with HHH 1 week after admission. Histology revealed an acute hepatitic
Tierra L. Mosher, Kathryn S. Czepiel, Matthew B. Neu, Andrea Carolina Cortes Fernandez, L. Walden Browne, Annie D. Niehaus, Roberto Gugig   +6 more
wiley   +1 more source

Suspected fibrosing cholestatic hepatitis in an immunocompetent child with hepatitis C: Case report

JPGN Reports, EarlyView.
Abstract A 12‐year‐old boy presented to our center with elevated aminotransferases, jaundice, right upper quadrant tenderness, and hepatomegaly. Evaluation revealed a highly elevated blood hepatitis C virus (HCV) ribonucleic acid (RNA) level, and liver biopsy showed canalicular and intrahepatic cholestasis, feathery degeneration of hepatocytes, and ...
Sara Bohon, Regino Gonzalez‐Peralta, Robert J. Fontana, Richard Cordle, Robin LeGallo, Frank DiPaola   +5 more
wiley   +1 more source