Results 31 to 40 of about 9,592 (229)
Human Embryonic Stem Cell-Derived Wilson’s Disease Model for Screening Drug Efficacy
Cells, 2020 Human pluripotent stem cells (hPSCs) including human embryonic stem cells (hESCs) and human-induced pluripotent stem cells (hiPSCs) have been extensively studied as an alternative cellular model for recapitulating phenotypic and pathophysiologic ...
Dongkyu Kim +13 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
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Plasmapheresis for Fulminant Wilson’s Disease Improves Mental Status and Coagulopathy
Case Reports in Hepatology, 2023 Wilson’s disease is a rare genetic condition that affects copper metabolism, resulting in tissue copper accumulation and resultant organ damage. We report a case of a young woman who presents with Wilson’s disease complicated by hemolysis, impaired ...
Quarshie Glover, William Nicholas Rose
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Advanced Functional Materials, EarlyView.Thioketal (TK) polymers are promising biomaterials due to their selective biodegradation by reactive oxygen species (ROS), but they respond slowly to physiologic doses of ROS. Here, the TK bond's pendant groups are modified to enhance the degradation of TK‐based implants both in vitro and in vivo.
Karina A. Bruce +6 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse +9 more
wiley +1 more source
Wilson’s disease in a child: a difficult path to diagnosis (clinical case)
Zdorovʹe RebenkaThe article presents data on the etiology, pathogenesis and clinical manifestations of Wilson’s disease, and also describes a diagnostically complex clinical case and own observation of a patient with Wilson’s disease. Wilson’s disease is a chronic liver
O.M. Вabadzhanian +4 more
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ПСЕВДОВИЛЬСОН-КОНОВАЛОВ — ВОЗВРАЩЕНИЕ К ПРИМАТУ КЛИНИЧЕСКОГО ДИАГНОЗА В ХХI ВЕКЕ
Архивъ внутренней медицины, 2015 Tremor disease Wilson’s is demands obligatory differential diagnosis with multiple sclerosis. The article presents a clinical case of mistaken diagnosis, “Wilson’s disease” rather than the diagnosis “multiple sclerosis” in young men.
З. А. Гончарова +2 more
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Atypical case of Wilson's disease with psychotic onset, low 24 hour urine copper and the absence of Kayser-Fleischer rings [PDF]
Vojnosanitetski Pregled, 2014 Introduction. Wilson's disease is typically manifested in two clinical forms, neurological and hepatic and in rare cases it starts with psychiatric symptoms exclusively. We presented a rare atypical case of Wilson's disease with psychotic onset.
Krstić Dragan +2 more
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Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
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Wilson’s Disease in an Elderly Patient
Canadian Journal of Gastroenterology, 1995 A 65-year-old man with Fanconi’s syndrome was investigated for the cause of chronic liver disease. Wilson’s disease was diagnosed based on the detection of bilateral Kayser-Fleischer rings, a low serum ceruloplasmin level, increased urine copper ...
Maziar Badii +3 more
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