Results 1 to 10 of about 2,527 (168)

ATP7B-maintained copper stores in myeloid progenitors are required for functional maturation of neutrophils. [PDF]

Cell Rep
Dev S, Wang Y, Jung M, Ma Y, Mani S, Kabin E, Yuda R, Dong Y, Ralle M, Hamilton JP, Lutsenko S.   +10 more
europepmc   +1 more source

Meta-Transcriptomic Response to Copper Corrosion in Drinking Water Biofilms. [PDF]

Microorganisms
Lu J, Struewing I, Ashbolt NJ.
europepmc   +1 more source

From Radiocopper to Cold Copper: Mechanistic Modeling and Simulation to Define Clinical Response Criteria and Biomarkers for VTX-801 in Wilson Disease. [PDF]

CPT Pharmacometrics Syst Pharmacol
Lindauer A, Benichou B, González Aseguinolaza G, Combal JP.   +3 more
europepmc   +1 more source

Cuproptosis: Mechanisms, biological significance, and advances in disease treatment-A systematic review. [PDF]

CNS Neurosci Ther
Pan C, Ji Z, Wang Q, Zhang Z, Wang Z, Li C, Lu S, Ge P.   +7 more
europepmc   +1 more source

Copper in Human Health and Disease: Insights from Inherited Disorders. [PDF]

Physiology (Bethesda)
Petruzzelli R, Polishchuk EV, Polishchuk RS.   +2 more
europepmc   +1 more source

Copper Trafficking in Caenorhabditis elegans : Copper Chaperone and Copper Transporting ATPase

Copper Trafficking in Caenorhabditis elegans : Copper Chaperone and Copper Transporting ATPase
openaire  

Function and Regulation of Human Copper-Transporting ATPases

Physiological Reviews, 2007
Copper-transporting ATPases (Cu-ATPases) ATP7A and ATP7B are evolutionarily conserved polytopic membrane proteins with essential roles in human physiology. The Cu-ATPases are expressed in most tissues, and their transport activity is crucial for central nervous system development, liver function, connective tissue formation, and many other ...
Svetlana, Lutsenko, Natalie L, Barnes, Mee Y, Bartee, Oleg Y, Dmitriev   +3 more
openaire   +4 more sources

Copper Transporting P-Type ATPases and Human Disease

Journal of Bioenergetics and Biomembranes, 2002
Copper transporting P-type ATPases, designated ATP7A and ATP7B, play an essential role in mammalian copper balance. Impaired intestinal transport of copper, resulting from mutations in the ATP7A gene, lead to Menkes disease in humans. Defects in a similar gene, the copper transporting ATPase ATP7B, result in Wilson disease.
Diane W, Cox, Steven D P, Moore
openaire   +2 more sources

Conservation of copper-transporting P(IB)-type ATPase function

BioMetals, 2010
Copper-transporting P(IB)-type ATPases are highly conserved, and while unicellular eukaryotes and invertebrates have only one, a gene duplication has occurred during vertebrate evolution. Copper-induced trafficking of mammalian ATP7A and ATP7B from the trans-Golgi Network towards the plasma membrane is critical for their role in copper homeostasis.
Southon, Adam, Palstra, Nickless, Veldhuis, Nicholas, Gaeth, Ann, Robin, Charles, Burke, Richard, Camakaris, James   +6 more
openaire   +3 more sources