Results 61 to 70 of about 5,188,381 (253)
Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl +6 more
wiley +1 more source
Insights into the management of Wilson’s disease
, 2017 Wilson’s disease is a rare, inherited autosomal recessive disease of copper metabolism, in which the causative gene, ATP7B , results in absent or reduced function of the ATP7B transporter important for biliary excretion of copper and incorporation of ...
Gideon M. Hirschfield +1 more
core +2 more sources
Arthritis Care &Research, Accepted Article.Objective High body mass index (BMI≥27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck +10 more
wiley +1 more source
Successful Photorefractive Keratectomy in a Case of Wilson’s Disease
, 2021 Purpose. To report a female with a history of Wilson’s disease who underwent a successful photorefractive keratectomy (PRK) for myopic correction. Case Presentation.
Hamid-Reza Heidarzadeh +1 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objectives This study synthesised the content and reporting completeness of published physical therapist‐led interventions for glenohumeral osteoarthritis (GHOA). Methods This systematic review undertook electronic database searches in PubMed, EMBASE, Cochrane, CINAHL and PEDro (until June 2025) for any peer‐reviewed articles/studies describing ...
Daha G Muhammad +5 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan +6 more
wiley +1 more source
ПСЕВДОВИЛЬСОН-КОНОВАЛОВ — ВОЗВРАЩЕНИЕ К ПРИМАТУ КЛИНИЧЕСКОГО ДИАГНОЗА В ХХI ВЕКЕ
Архивъ внутренней медицины, 2015 Tremor disease Wilson’s is demands obligatory differential diagnosis with multiple sclerosis. The article presents a clinical case of mistaken diagnosis, “Wilson’s disease” rather than the diagnosis “multiple sclerosis” in young men.
З. А. Гончарова +2 more
doaj +1 more source
Human Embryonic Stem Cell-Derived Wilson’s Disease Model for Screening Drug Efficacy
Cells, 2020 Human pluripotent stem cells (hPSCs) including human embryonic stem cells (hESCs) and human-induced pluripotent stem cells (hiPSCs) have been extensively studied as an alternative cellular model for recapitulating phenotypic and pathophysiologic ...
Dongkyu Kim +13 more
doaj +1 more source
Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders
Advanced Science, EarlyView.BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley +1 more source
Wilson’s Disease—Genetic Puzzles with Diagnostic Implications
, 2023 (1) Introduction: Wilson’s disease (WND) is an autosomal recessive disorder of copper metabolism. The WND gene is ATP7B, located on chromosome 13. WND is characterized by high clinical variability, which causes diagnostic difficulties.
Maria Bendykowska +5 more
core +1 more source