Results 131 to 140 of about 463,017 (306)

Unsteady simulation of flow in micro vertical axis wind turbine [PDF]

, 2010
Though wind turbines and windmills have been used for centuries, the application of aerodynamics technology to improve reliability and reduce costs of wind-generated energy has only been pursued in earnest for the past 40 years.
BOIS, Gérard, BAYEUL-LAINÉ, Annie-Claude   +1 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Combination of High- and Low-Rate GPS Receivers for Monitoring Wind-Induced Response of Tall Buildings. [PDF]

Sensors (Basel), 2018
Yi Z, Kuang C, Wang Y, Yu W, Cai C, Dai W.   +5 more
europepmc   +1 more source

Human perception and tolerance of wind-induced building motion

, 2013
Wind-induced building motion can interfere with building occupants’ daily activities and general well-being. However, human perception of motion and tolerance of wind-induced tall building vibration are essentially a subjective assessment.
Kwok, Kenny C. S. (R14040)
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Integrated Aerodynamic–Structural Validation Framework for Wind-Induced Load Assessment

Applied Sciences
Understanding wind–structure interaction (WSI) in low-rise buildings remains a significant challenge in wind and structural engineering, particularly under highly turbulent and non-stationary wind phenomena such as downbursts and tornado-like vortices ...
Tomasz Lamparski, Maciej Dutkiewicz
doaj   +1 more source

An experimental and finite element study of the low-cycle fatigue failure of a galvanised steel lighting column

, 2009
This paper presents the results of a low-cycle fatigue test on a lighting column. The wind induced vibration phenomena responsible for low cycle fatigue in such structures is discussed and the failure mechanism is examined.
Taylor, Ian, Wood, James, Alexander, Louise A.   +2 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Reduction of wind-induced vibration of tall buildings using suspended mass pendulums

, 2014
This paper is aimed at the investigation of using suspended mass pendulums to reduce Wind-induced vibration of tall buildings. The tall building is modeled as a shear building with the same floor mass and lateral stiffness for each story, and the ...
Yao, J. D.; Hsu, T. C.; Tuan, Alex Y.
core