Results 121 to 130 of about 463,017 (306)

Extreme-Value Combination Rules for Tower–Line Systems Under Non-Gaussian Wind-Induced Vibration Response

open access: yesBuildings
Currently, extreme response analysis of tower–line systems typically assumes each component response follows a stationary Gaussian process. However, actual structural responses often exhibit significant non-Gaussian characteristics, potentially ...
Shuang Zhao   +6 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Influence Analysis of Wind Suction Resistance Devices on Dynamic Performance and Wind-Induced Response of Long-Span Flexible Photovoltaic Arrays

open access: yes南方能源建设
[Objective] The large-span flexible photovoltaic support array, characterized by its lightweight and low fundamental frequency, is a typical wind-sensitive structure.
Xiaofeng GE   +7 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Structural Response Analysis and Comfort Evaluation of Residential Buildings: A Combined Wind Tunnel and FEM Approach

open access: yesBuildings
With global urbanization accelerating, high-rise buildings have become a common feature in the urban landscape, especially in coastal cities, where they encounter unique wind-load challenges.
Xinxin Zhang, Xiang Yuan Zheng, Kun Lin
doaj   +1 more source

Wind-induced responses of a tall building with a double-skin facade system

open access: yes, 2017
To date the engineering community has seen double-skin facade systems as non-structural elements on buildings for the aesthetic desire, improving the indoor environment, reducing the energy use, and even improving acoustics in buildings.
Tse, Kam-Tim   +3 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Physics‐Informed Neural Networks for Modeling the Martian Induced Magnetosphere

open access: yesGeophysical Research Letters
Understanding the magnetic field environment around Mars and its response to upstream solar wind conditions provide key insights into the processes driving atmospheric ion escape.
Jiawei Gao   +8 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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