Results 101 to 110 of about 359,992 (302)

Numerical Simulation of Wind-Induced Vibration Response Characteristics of High-Rise Buildings with Podiums

Buildings
High-rise building structures with podiums are widely present, and establishing a fast numerical prediction method to evaluate their wind-induced response characteristics is of great significance for engineering applications.
Guangbiao Jiang, Zeyan Chen, Hongxi Qin, Linlei Dong, Ao Tang   +4 more
doaj   +1 more source

Dynamic response of two composite prop-fan models on a nacelle/wing/fuselage half model [PDF]

Results are presented for blade response wind tunnel tests of two 62.2 cm diameter Prop-Fan (advanced turboprop) models with swept and unswept graphite/epoxy composite blades.
Brooks, Bennett M., Smith, Arthur F.
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Shape sensitivity analysis of wing static aeroelastic characteristics [PDF]

A method is presented to calculate analytically the sensitivity derivatives of wing static aeroelastic characteristics with respect to wing shape parameters.
Barthelemy, Jean-Francois M., Bergen, Fred D.   +1 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Wind-Resistant Configuration of Double-Layer Cable-Supported Flexible Photovoltaic Array Based on Interference Effect Analysis

Energies
This study investigates the wind-resistant configuration of a seven-row single-span double-layer cable-supported photovoltaic (PV) array through conducting systematic analysis of the interference effect.
Yi Tang, Yuxiang Wu, Wei Hao, Yalin Yan, Honghai Li   +4 more
doaj   +1 more source

Adaptive feedforward control design for gust loads alleviation and LCO suppression

, 2014
An adaptive feedforward controller is designed for gust loads alleviation and limit cycle oscillations suppression. Two sets of basis functions, based on the finite impulse response and modified finite impulse response approaches, are investigated to ...
Da Ronch, A., Ghandchi-Tehrani, Maryam, Li, E., Wang, Yongzhi   +3 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Study on Wind Vibration Response and Coupling Effect of Transmission Tower-Line System Under Downburst

IEEE Access
Downburst is a type of near-surface short-term destructive strong wind that significantly affects wind-sensitive flexible structures like transmission tower-line systems.
Yongli Zhong, Yichen Liu, Shun Li, Zhitao Yan, Xinpeng Liu   +4 more
doaj   +1 more source