Results 51 to 60 of about 9,210 (222)

From Generation to Reuse: A Circular Economy Strategy Applied to Wind Turbine Production

Designs
The environmental impact of wind turbine rotor blades, both during manufacturing and at the end of their life cycle, can be significant. The aim of this study was to define and test a methodology for recycling the waste resulting from their production ...
Ana Rita Caramelo, Paulo Santos, Tânia Miranda Lima   +2 more
doaj   +1 more source

Suppression of transverse vibration of elevator rope using vertical vibration of counterweight

Nihon Kikai Gakkai ronbunshu, 2015
An elevator rope for high-rise building is forcibly excited by the displacement of the building caused by earthquakes and wind forces. In high-rise building, the elevator rope may resonate with the natural frequency of the building; hence, effective ...
Ibuki HIROSE, Hiroyuki KIMURA, Kou OGAWA
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Modeling the relationship between textile fabric surface morphology and air drag force at varying reynolds numbers

Discover Materials
This study is a 100% experimental-theoretical framework for the analysis and control of aerodynamic drag of textile fabrics with engineered surface topology.
Magdi El Messiry, Abeer Mohamed
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

An Innovative Green Dust Suppressant for Dry Climate Mining Areas in a Copper–Nickel Mine: Integration of Moisture Retention and Erosion Resistance

Atmosphere
Mine ramps, serving as a critical transportation hub in underground mining activities, are beset by severe issues of dust pollution and secondary dust generation.
Zijun Li, Zhe Zhou, Yu Xu, Yin Chen
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Numerical Analysis of FOWT Dynamics with Fully Coupled and Decoupled Methods: A Comparative Study

Energies
The numerical analysis technique is one of the primary methods for the design and development of floating offshore wind turbines (FOWTs). This study presents a detailed investigation into the influences of fully coupled and decoupled numerical analysis ...
Shi Liu, Yi Yang, Tao Tao, Zheng Huang, Wei Jiang, Chaohe Chen, Xinkuan Yan   +6 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source