Results 71 to 80 of about 9,061,461 (261)
Motion-induced wind forces of a slender prism
, 2017 The motion-induced wind forces of a slender prism were investigated using a forced vibration technique. The prism was driven to oscillate by an actuator in cross-wind direction and the unsteady distributed pressures, under different wind velocities and ...
Chen, Zhengshun +2 more
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
AtmosphereMine ramps, serving as a critical transportation hub in underground mining activities, are beset by severe issues of dust pollution and secondary dust generation.
Zijun Li, Zhe Zhou, Yu Xu, Yin Chen
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Advanced Wind Turbine Program Next Generation Turbine Development Project: June 17, 1997--April 30, 2005 [PDF]
, 2006 This document reports the technical results of the Next Generation Turbine Development Project conducted by GE Wind Energy LLC. This project is jointly funded by GE and the U.S. Department of Energy's National Renewable Energy Laboratory.The goal of this
GE Wind Energy, LLC
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한국해양공학회지Mooring systems for modular floating structures (MFSs) in shallow water require designs that account for a limited water depth, restricted footprint, and coupled responses among floaters, connectors, and mooring lines.
Min Ju Maeng, Dong Hee Choi, Bo Woo Nam
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Stratified Wind Geometries of GRS 1915+105: Density Profiles and Radii
The Astrophysical JournalThe low-mass X-ray binary GRS 1915+105 exhibits dramatic spectral and flux variability, often accompanied by highly ionized outflows. In this work, we analyze four archival Chandra/HETG observations spanning over a decade, which vary greatly in their ...
Noa Keshet +3 more
doaj +1 more source
Numerical Analysis of FOWT Dynamics with Fully Coupled and Decoupled Methods: A Comparative Study
EnergiesThe numerical analysis technique is one of the primary methods for the design and development of floating offshore wind turbines (FOWTs). This study presents a detailed investigation into the influences of fully coupled and decoupled numerical analysis ...
Shi Liu +6 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source