Results 71 to 80 of about 103,722 (307)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Geomagnetic storms driven by ICME- and CIR-dominated solar wind. [PDF]

open access: yes, 2006
The interaction of the solar wind and the Earth's magnetosphere is complex and the phenomenology of the interaction is very different for solar wind dominated by interplanetary coronal mass ejections (ICMEs) compared to solar wind dominated by corotating
Liemohn, M. W.   +10 more
core   +1 more source

Wind Source Localization System Based on a Palm-Sized Quadcopter

open access: yesApplied Sciences
In this study, we implemented a compact wind direction sensor on a palm-sized quadcopter to achieve wind source localization (WSL). We designed an anemotaxis algorithm based on the sensor data and experimentally validated its efficacy.
Keisuke Yokota   +2 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Possible biases in wind speed measurements from merchant ships [PDF]

open access: yes, 2004
Wind speed measurements obtained from ship-mounted anemometers are biased by the presence of the ship which distorts the airflow to the anemometer. Until recently this bias had only been quantified for a few well-exposed anemometer sites on individual ...
Yelland, M.J., Moat, B.I., Molland, A.F.
core  

Three-Dimensional Wind Measurement Based on Ultrasonic Sensor Array and Multiple Signal Classification

open access: yesSensors, 2020
The wind power industry continues to experience rapid growth worldwide. However, the fluctuations in wind speed and direction complicate the wind turbine control process and hinder the integration of wind power into the electrical grid.
Bian Ma   +5 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Additional acceleration of solar-wind particles in current sheets of the heliosphere [PDF]

open access: yes, 2015
Particles of fast solar wind in the vicinity of the heliospheric current sheet (HCS) or in a front of interplanetary coronal mass ejections (ICMEs) often reveal very peculiar energy or velocity profiles, density distributions with double or triple peaks,
V. Zharkova   +4 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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