Results 111 to 120 of about 1,957,794 (246)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Force Characteristics of Sluice Structure in Coastal Area Under Wind Load
Renmin ZhujiangThis paper takes the sluice of the main channel on the east side of East Airport Road, Jinwan Coastal Business District, Zhuhai City, Guangdong Province as an example.
ZHANG Jian, YANG Jialin, YANG Jie
doaj
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Jixie chuandong, 2017 With the gradual popularization and maturity of wind energy resources exploitation and utilization technology,the installation and running environment of large wind turbine gradually develop from conventional flat terrain to complex terrain,which result ...
Wei Yufeng +3 more
doaj
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Pedestrian level wind environment around isolated buildings resulted from twisted wind profiles
, 2015 The pedestrian-level wind environment influenced by twisted wind profiles were evaluated through a series of wind tunnel tests. In the tests, more than 200 Irwin sensors were installed to measure the wind speeds at pedestrian level around five isolated ...
Tse, Kam-Tim +3 more
core
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
An analytical model for along wind design wind load of tall buildings
, 2013 An analytical model for tall buildings’ alongwind Equivalent Static Wind Loads is proposed. The basic assumptions, procedures and the parameters used in this model are mainly based on the results of wind tunnel investigation.
Cheng, Chii-Ming; Tsai, Ming-Shu; Lo, Yuan-Lung
core
Power system stability enhancement using wind–battery hybrids in the GADA Special Economic Zone
Academia Green EnergyThe demand for reliable and sustainable energy has led to the development of hybrid power solutions to improve stability with multiple energy sources.
Meskerem Tadesse Gebre, Getachew Biru
doaj +1 more source