Results 131 to 140 of about 1,957,794 (246)
Wind Load Factors for Use in the Wind Tunnel Procedure. [PDF]
ASCE ASME J Risk Uncertain Eng Syst A Civ Eng, 2017 Simiu E, Pintar AL, Duthinh D, Yeo D.
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Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Motion-induced wind forces of a slender prism
, 2017 The motion-induced wind forces of a slender prism were investigated using a forced vibration technique. The prism was driven to oscillate by an actuator in cross-wind direction and the unsteady distributed pressures, under different wind velocities and ...
Chen, Zhengshun +2 more
core
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
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Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Effect of Turbulence Intensity on Megawatt Wind Turbines
Kongzhi Yu Xinxi Jishu, 2013 Effect of turbulence intensity on wind turbines is analyzed in this paper. Simulation has been conducted for limit load, fatigue load and performance of wind turbines at three different turbulence intensity I15= 0.18,0.16,0.14 by taking 1 650 kW variable
OUYANG Hua +4 more
doaj
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Wind Power Development: Opportunities and Challenges [PDF]
In this study, the prospects of wind power at the global level are reviewed. Existing studies indicate that the earth’s wind energy supply potential significantly exceeds global energy demand.
Govinda R. Timilsina +1 more
core
Investigation of wind load behavior on hip roof structures subjected to Tornado-induced flow. [PDF]
PLoS OneHao X, Jia Y, Wang X, Cao W, Zhang Z.
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