Results 141 to 150 of about 66,305 (312)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Base-load cycling on a system with significant wind penetration

open access: yes
Certain developments in the electricity sector may result in suboptimal operation of base-load generating units in countries worldwide. Despite the fact they were not designed to operate in a flexible manner, increasing penetration of variable power ...
Troy, Niamh   +2 more
core  

POWER CONDITIONING UNIT FOR SMALL SCALE HYBRID PV-WIND GENERATION SYSTEM [PDF]

open access: yes, 2011
Small-scale renewable energy systems are becoming increasingly popular due to soaring fuel prices and due to technological advancements which reduce the cost of manufacturing.
AHMED-MAHMOUD, ASHRAF
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The Economics of Wind Power with Energy Storage [PDF]

open access: yes
We develop a nonlinear mathematical optimization program for investigating the economic and environmental implications of wind penetration in electrical grids and evaluating how hydropower storage could be used to offset wind power intermittence.
Pablo Benitez   +2 more
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Wind power in forests: Winds and effects on loads

open access: yes, 2013
I projektet V-312, Vindkraft i skog, har forskare och en doktorand vid Uppsala universitet, WeatherTech Scandinavia, Kungliga tekniska högskolan (KTH), DTU Wind Energy i Danmark och Teknikgruppen samarbetat. I projektet har det gjorts mätningar med hög vertikal upplösning av turbulensen i atmosfären, även ned mellan träden, syftande till att möjliggöra
Bergström, Hans   +9 more
openaire   +2 more sources

Power system stability enhancement using wind–battery hybrids in the GADA Special Economic Zone

open access: yesAcademia Green Energy
The demand for reliable and sustainable energy has led to the development of hybrid power solutions to improve stability with multiple energy sources.
Meskerem Tadesse Gebre, Getachew Biru
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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