Results 81 to 90 of about 288,653 (304)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Mass‐loaded Winds

open access: yesThe Astrophysical Journal, 1996
This paper explores the steady state behavior of mass-loaded winds. The topology of the critical point that results from the slowing of the wind is a function of the local slope of the mass-loading function. Mass-loading functions that increase sufficiently rapidly with radius as well as gravitational force can cause the steady state approximation to ...
openaire   +1 more source

Large Telescope Wind Loading [PDF]

open access: yesInternational Astronomical Union Colloquium, 1984
One important large telescope design study area is the dynamic image degradation caused by wind forces upon various telescope structures and optical elements. The need to establish rapid thermal equilibration with the observatory environment further complicates the wind exposure problem.
openaire   +1 more source

Comparison of computer codes for calculating dynamic loads in wind turbines [PDF]

open access: yes
The development of computer codes for calculating dynamic loads in horizontal axis wind turbines was examined, and a brief overview of each code was given.
Spera, D. A.
core   +2 more sources

Design and Testing of a Structural Monitoring System in an Almería-Type Tensioned Structure Greenhouse [PDF]

open access: yes, 2020
Greenhouse cultivation has gained a special importance in recent years and become the basis of the economy in south-eastern Spain. The structures used are light and, due to weather events, often collapse completely or partially, which has generated ...
Marín Membrive, Patricia   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Fatigue Load Estimation through a Simple Stochastic Model

open access: yesEnergies, 2014
We propose a procedure to estimate the fatigue loads on wind turbines, based on a recent framework used for reconstructing data series of stochastic properties measured at wind turbines. Through a standard fatigue analysis, we show that it is possible to
Pedro G. Lind   +3 more
doaj   +1 more source

Natural environment analysis [PDF]

open access: yes
Qualitative analyses (and quantitatively to the extend possible) of the influence of terrain features on wind loading of the space shuttle while on the launch pad, or during early liftoff, are presented.

core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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