Results 101 to 110 of about 39,461 (310)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Fatigue Load Estimation through a Simple Stochastic Model

open access: yesEnergies, 2014
We propose a procedure to estimate the fatigue loads on wind turbines, based on a recent framework used for reconstructing data series of stochastic properties measured at wind turbines. Through a standard fatigue analysis, we show that it is possible to
Pedro G. Lind   +3 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Wind loads on contemporary Australian housing

open access: yes, 2015
Contemporary 1 and 2-storey houses being built in and around Brisbane and Melbourne have been surveyed and representative houses defined. Wind tunnel studies on 1/50 scale wind tunnel models are used to determine the spatial and temporal variation in ...
Henderson, D.J.   +3 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Drivetrain availability in offshore wind turbines

open access: yes, 2014
As part of the drive train and generator track this paper will present the results of a comparative study on the availability of offshore wind turbine drive train types. Twelve different drive train types will be compared.
Julian Feuchtwang   +7 more
core  

Estimation of stresses in atmospheric ice during aeolian vibration of power transmission lines [PDF]

open access: yes, 2010
Aeolian vibration in bare and iced cable was simulated using the theory of cable vibration. High frequency vibration creates stresses in the cable and consequently in the ice covering that cable, which may result in ice failure and eventually ice ...
Kermani, Majid   +5 more
core   +1 more source

Wind and Wave Disturbances Compensation to Floating Offshore Wind Turbine Using Improved Individual Pitch Control Based on Fuzzy Control Strategy

open access: yesAbstract and Applied Analysis, 2014
Due to the rich and high quality of offshore wind resources, floating offshore wind turbine (FOWT) arouses the attentions of many researchers. But on a floating platform, the wave and wind induced loads can significantly affect power regulation and ...
Feng Yang   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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