Results 111 to 120 of about 935,111 (345)
Solar cycle evolution of the solar wind in three dimensions [PDF]
, 1983 Measurements of the solar wind speed both in and out of the ecliptic are presented for 1971-82. The speed estimates, which were made with the interplanetary scintillation system at UC San Diego, have been compared to in situ for large, slowly evolving ...
Coles, W. A., Rickett, B. J.
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Wind Mapping of Malaysia Using Ward’s Clustering Method
EnergiesMalaysian wind maps used in wind analysis and engineering design are dated back to the last 50 years of wind data. Cotemporally, the mean wind speed was used as the basic wind design and due to changes in the weather condition worldwide, wind monitoring ...
Amar Azhar, Huzaifa Hashim
doaj +1 more source
Impact of Wind Speed and Direction and Key Meteorological Parameters on Potential Pesticide Drift Mass Loadings from Sequential Aerial Applications [PDF]
, 2019 Dean Desmarteau +3 more
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Experimental Study of Wind Booster Addition for Savonius Vertical Wind Turbine of Two Blades Variations Using Low Wind Speed [PDF]
, 2019 Eflita Yohana +4 more
openalex +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source