Results 91 to 100 of about 948,844 (344)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Airflow distortion at instrument sites on the RRS James Clark Ross during the WAGES project [PDF]

open access: yes, 2015
Wind speed measurements obtained from anemometers mounted on ships are prone to systematic errors caused by the distortion of the airflow around the ship's hull and superstructure.
Moat, B.I., Yelland, M.J.
core  

On the shape of barchan dunes

open access: yes, 2005
Barchans are crescent-shaped sand dunes forming in aride regions with unidirectional wind and limited sand supply. We report analytical and numerical results for dune shapes under different environmental conditions as obtained from the so-called `minimal
Bagnold R A   +14 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Assessment of wind energy potential of two sites in North-East, Nigeria [PDF]

open access: yes, 2011
The study is used to assess the wind energy potential of Maiduguri and Potiskum, two sites in North-East, Nigeria. 21 years (1987e2007) monthly mean wind data at 10 m height were assessed from the Nigeria Meteorological department and subjected to 2 ...
Ajayi, O. O.   +3 more
core   +1 more source

Three-dimensional Evolution of Solar Wind during Solar Cycles 22-24

open access: yes, 2012
This paper presents the analysis of 3D evolution of solar wind density turbulence and speed at various levels of solar activity between solar cycles 22 and 24.
Abramenko   +18 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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