Results 81 to 90 of about 3,142,824 (343)

Wind field and pressure characteristics on wind turbine surface under moving thunderstorms

Energy Reports, 2023
Based on computational fluid dynamics and large-eddy simulation technologies, a numerical simulation method of a moving thunderstorm field is established by considering the impinging jet model.
Chuncheng Liu, Siyu Ma, Zhao Yan, Chengbo Li   +3 more
doaj  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Design of mine opposed wind speed and direction sensor

Gong-kuang zidonghua
In response to the current problems of high startup wind speed, complex design schemes, and inability to accurately measure the average wind speed of the entire section of the roadway using wind speed sensors, based on the principle of ultrasonic opposed
AN Sai, ZHAO Zhonghui, ZHANG Lang, LI Wei, PENG Ran   +4 more
doaj   +1 more source

Wind Speed Prediction of IPSO-BP Neural Network Based on Lorenz Disturbance

IEEE Access, 2018
Accurate wind power prediction provides significant guarantee for power grid dispatching, and wind speed prediction, as the basic link of wind power forecasting, has crucial theoretical research significance and practical application value. In this paper,
Yagang Zhang, Bing Chen, Yuan Zhao, Guifang Pan   +3 more
semanticscholar   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Fully-coupled modeling and analysis of the influence of anti-icing bleed air system of engine inlet duct on compressor performance

Case Studies in Thermal Engineering
A fully-coupled method that integrates the compressor, inlet duct and anti-icing bleed air system (AI-BAS) was established to offer a quick prediction of the effects of anti-icing bleeding on compressor performance, facilitating the development of a ...
Zuojun Wei, Cheng Li, Guangming Ren, Xiaohua Gan   +3 more
doaj  

Assessment of onshore wind energy potential under temperate continental climate conditions

Energy Reports, 2022
Using the Weibull distribution function, the study presents a statistical evaluation of wind characteristics and onshore wind power potential under temperate continental climate conditions.
Spiru Paraschiv, Lizica Simona Paraschiv, Alexandru Serban, Anisoara Gabriela Cristea   +3 more
doaj  

CFD and Wind Tunnel Analysis for Mounted-Wind Turbine in a Tall Building for Power Generation

Journal of Mechatronics, Electrical Power, and Vehicular Technology, 2014
A mounted wind turbine on the top of a tall building may provide high wind power in regions of high wind speed and low turbulence. The objective of this study is to evaluate wind speed on roof top models to optimize the wind turbine performance for power
Dany Perwita Sari, Kang-Pyo Cho
doaj   +1 more source