Results 111 to 120 of about 582,160 (304)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Two-layer model of wind-driven circulation in the Antarctic Ocean [PDF]

open access: yes, 2003
In this study, we investigate the wind-driven circulation in the Antarctic Ocean using a primitive two-layer model with realistic topography. A prominent feature of steady circulation driven by the annual mean wind stress is a clockwise(cyclonic ...
Katsumata,Katsurou   +2 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

On the correct surface stress for the prediction of the wind wave field and the storm surge in the Northern Adriatic Sea [PDF]

open access: yes, 1998
This paper discusses which formulation of the surface stress over the sea determines the most accurate prediction of the wind wave field and storm surge in the Northern Adriatic Sea.
Bergamasco, A.   +4 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Wind-stress misalignment in the presence of swells in the Bay of Bengal

open access: yesFrontiers in Marine Science
This study investigates the directional characteristics of momentum flux, τ, under diverse wind-wave conditions in the Bay of Bengal (BoB). Using high-frequency data from an eddy covariance flux system deployed on a moored buoy, we identify various cases
Abhijith Raj   +7 more
doaj   +1 more source

Wind-induced Stresses on Water Surfaces: A Wind-tunnel Study [PDF]

open access: yesAustralian Journal of Physics, 1963
A laboratory wind tunnel has been used to study the effect of wind on a water surface. The surface shearing stress 7'0 and the slope of the surface induced by wind have been measured. Values of the surface stress, in good agreement with each other, have been obtained from: (a) the velocity profile of the wind above the water surface, (b) the measured ...
openaire   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Estimating Wind Stress at the Ocean Surface From Scatterometer Observations [PDF]

open access: yes
—Wind stress is the most important ocean forcing for driving tropical surface currents. Stress can be estimated from scatterometer-reported wind measurements at 10 m that have been extrapolated to the surface, assuming a neutrally stable atmosphere and ...
David G. Long   +4 more
core  

Antisymmetric wind stress fields and parity transformation of the correction streamfunctions in the western boundary layer of oceanic basins [PDF]

open access: yes, 1997
Most models of the single-gyre, wind-driven oceanic circulation resort to wind stress fields that are strictly antisymmetric under a parity transformation with respect to a mid basin latitude.
Crisciani, F.
core  

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