Results 41 to 50 of about 617,994 (259)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

”Windows of Synchronization” and ”Non-chaotic Windows” [PDF]

ESAIM: Proceedings and Surveys, 2014
The dynamic of a chaotic dynamical system changes if we couple it together with another one. The changes depend on the dynamic of the systems and on the way the coupling is made. The strength of the coupling is controlled by the coupling strength constant. For some values of this constant synchronization may occur, defining a “window of synchronization”
Lopes Luís Mário, Fernandes Sara, Grácio Clara   +2 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Using portable monitoring for heterogeneous clusters on Windows and Linux operating systems

Journal of Computer Science and Technology, 2003
This paper describes the advances obtained with the XPVM-W95 2.0, a novel monitoring tool for parallel applications that employ PVM-W95 (PVM for Windows) as well as PVM for Linux.
Daniel Kikuti, Paulo S. L. Souza, Simone R. S. Souza   +2 more
doaj  

Community perceptions and acceptability of insecticide-treated screens for mosquito proofing of unimproved houses in Chalinze district, Tanzania: a mixed-methods study

Frontiers in Malaria
BackgroundUnimproved housing is a risk factor for malaria. Therefore, netting incorporated with deltamethrin and piperonyl butoxide, supplied as a roll to screen opened eaves, windows, and holes in the walls of unimproved houses, could offer protection ...
Fadhila Kihwele, Olukayode G. Odufuwa, Olukayode G. Odufuwa, Olukayode G. Odufuwa, Olukayode G. Odufuwa, Joseph B. Muganga, Emmanuel Mbuba, Emmanuel Mbuba, Emmanuel Mbuba, Rose Philipo, Jason Moore, Jason Moore, Jason Moore, Ole Skovmand, Rune Bosselmann, John Bradley, Sarah Moore, Sarah Moore, Sarah Moore, Sarah Moore, Zawadi Mageni Mboma, Zawadi Mageni Mboma   +21 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

DESIGNING A WINDOWS PROGRAM FOR CONTROLLING DC-MOTORS USING MICROSOFT VISUAL STUDIO AND ARDUINO IDE

Journal of Industrial Design and Engineering Graphics, 2019
This case study wishes to highlight the advantages of using a Windows based PC to control a DC Motor for applications in small projects, the DC Motor being driven by an Arduino Uno board.
Theodor - Andrei Popescu, Ioana Teodora Costache   +1 more
doaj   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source