Results 81 to 90 of about 427,006 (340)
A surgical model of short bowel syndrome induces a long-lasting increase in pancreatic beta-cell mass [PDF]
, 2015 Several surgical techniques are used nowadays as a severe treatment for obesity and diabetes mellitus type 2. These techniques are aggressive due to drastic changes in the nutrient flow and non-reversible modifications on the digestive tube.
Aguilar Diosdado, Manuel +6 more
core +2 more sources
Aortic depressor nerve differences between Wistar and Wistar‐Kyoto rats
The FASEB Journal, 2012 Previous reports from our laboratory [1, 2, 3] showed differences on the morphology of the aortic depressor nerve (ADN) between normotensive Wistar‐Kyoto (WKY) and spontaneously hypertensive rats (SHR). The aim of the present study was to investigate if there are morphological and morphometric differences on the AND of two different normotensive rats ...
Milena Menezes de Amorim +4 more
openaire +2 more sources
Wistar Diabetic Fatty Rat [PDF]
ILAR Journal, 1990 Wistar diabetic fatty (WDF/Ta-/a) rats were developed by Ikeda et al. (1981) to provide a rat model of non-insulindependent diabetes mellitus (NIDDM). Human NIDDM is typically characterized by adult onset and varying degrees of obesity, hyperglycemia, hyperinsulinemia, insulin resistance, glucose intolerance, and peripheral neuropathy.
David B. West +3 more
openaire +2 more sources
Targeted Expansion of Treg Cells to Induce Immune Tolerance after Kidney Transplantation
Advanced Science, EarlyView.A dual‐targeting nanoparticle platform that selectively engages graft stromal cells via CD248 receptors while employing kidney‐ specific promoters (NPHS2) to drive localized IL‐ 2/TGF‐βexpression is developed. This approach achieves three therapeutic objectives:1) intragraft Treg polarization without systemic cytokine exposure;2) reduced dependence on ...
Tong Lu +18 more
wiley +1 more source
Targeting CARM1 in ovarian cancer with EZH2 and PARP inhibitors
Molecular & Cellular Oncology, 2020 Coactivator-associated arginine methyltransferase 1 (CARM1)-expressing high-grade serous ovarian cancers are characterized by poor prognosis and limited therapeutic options.
Sergey Karakashev, Rugang Zhang
doaj +1 more source
Adolescent methylphenidate treatment differentially alters adult impulsivity and hyperactivity in the Spontaneously Hypertensive Rat model of ADHD [PDF]
, 2016 Impulsivity and hyperactivity are two facets of attention deficit/hyperactivity disorder (ADHD). Impulsivity is expressed as reduced response inhibition capacity, an executive control mechanism that prevents premature execution of an intermittently ...
Bardo, M. T. +3 more
core +1 more source
Ultrastructural investigation of the aortic depressor nerve in Wistar and Wistar‐Kyoto rats
The FASEB Journal, 2012 Ultrastructural study of the aortic depressor nerve (ADN) [1] showed differences on the morphology and morphometry between normotensive Wistar‐Kyoto (WKY) and spontaneously hypertensive rats (SHR), particularly in the number of unmyelinated fibers. The aim of the present study was to investigate if there are ultrastructural differences on the AND of ...
Vânia Alice de Aguiar Mendes +4 more
openaire +2 more sources
Advanced Science, EarlyView.This work found that early‐stage insulin sensitization but late‐stage insulin resistance in prenatal caffeine exposure (PCE)‐ induced intrauterine growth restriction (IUGR) offspring may be related to the hepatic AGEs accumulation via intrauterine GR/miR‐1224 programming by glucocorticoids.
Yongguo Dai +5 more
wiley +1 more source
Oral Intake of Sardinella Longiceps Oil the Decrease of Tnf-? and Il-6 Levels in Atherosclerotic Wistar Rat [PDF]
, 2011 Lifestyle changes to consumption of variegated instant food may be associated several heath hazards, such as obesity, dyslipidemia, and atheroschlerosis.
Astawa, I. N. (I) +3 more
core
Female and male Wistar rats (Rattus norvegicus) discriminate diets according to energetic quantity [PDF]
, 2020 The food choice of animals is influenced by several factors including the quantity and nutrients available. It is not known, however, whether faced with alternatives that present the same amount of food, with similar flavor and obtained with the same ...
Aragon, Davi Casadele +4 more
core