Results 141 to 150 of about 237,978 (340)

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

ESC Heart Failure, EarlyView.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori, Sergio Davinelli, Armando Ferrera, Alessandro Medoro, Carlo Barsali, Allegra Battistoni, Maurizio Volterrani, Massimo Volpe, Luciano Saso, Speranza Rubattu   +9 more
wiley   +1 more source

The diabetic syndrome of the ?BB? Wistar rat: Possible relevance to Type 1 (insulin-dependent) diabetes in man [PDF]

, 1982
Errol B. Marliss, A. F. Nakhooda, Philippe Poussier, Anders A. F. Sima   +3 more
openalex   +1 more source

Morphometric alterations to the rat spleen following formaldehyde exposure [PDF]

, 2008
Formaldehyde is commonly used in the production of various industrial and medical products. At room temperature formaldehyde easily evaporates. Exposure to formaldehyde can be hazardous to human health.
Azarhoush, R., Davarian, A., Fazeli, S.A., Ghafari, S., Gharravi, A.M., Golalipour, M.J., Kord, H.   +6 more
core  

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Quantitative analysis of serum metabolites in a rat model of Alzheimer’s disease

Frontiers in Aging Neuroscience
ObjectiveOXYS rats are a unique animal model of sporadic Alzheimer’s disease (AD) that demonstrates all the key signs of AD in humans. Studying metabolic processes in OXYS rats in comparison with control Wistar rats can contribute to understanding the ...
Anton A. Smolentsev, Anton A. Smolentsev, Darya V. Telegina, Nataliya G. Kolosova, Yuri P. Tsentalovich, Olga A. Snytnikova   +5 more
doaj   +1 more source

Some Observations upon the Mitotic and Meiotic Divisions in the Wistar Rat

, 1937
William Bryden
openalex   +2 more sources

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

Some Observations upon the Mitotic and Meiotic Divisions in the Wistar Rat. III

, 1936
William Bryden
openalex   +2 more sources

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension [PDF]

, 2013
Abdala, Ana P, Hendy, Emma B, Marvar, Paul, McBryde, Fiona D, Moraes, Davi J A, Paton, Julian F R, Pijacka, Wioletta, Sobotka, Paul A   +7 more
core   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source