Progress in bone tissue engineering biomaterials: Development, challenges, and prospects
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang +7 more
wiley +1 more source
Development of anatomically variable digital Wistar rat phantoms for small animal imaging research. [PDF]
Segars HE +8 more
europepmc +1 more source
An Experimental Study on the Protective Effect of Memantine in Noise‐Induced Hearing Loss
ABSTRACT Objective This study examined the potential protective effects of memantine, an N‐methyl‐D‐aspartate (NMDA) receptor antagonist, against acoustic trauma (AT) in guinea pigs, using electrophysiological and histopathological analyses. Methods Thirty guinea pigs with normal hearing were divided into six groups (n = 5 per group): Group 1 (control),
Begüm Arda +6 more
wiley +1 more source
<i>Ficus religiosa</i> leaf extract mitigates the neurofibrillary tangles and amyloid plaques in aluminium chloride exposed Wistar rat brain. [PDF]
Massand A, Rai R, Rai AR, Joy T.
europepmc +1 more source
ABSTRACT This study evaluated whether the incorporation of sodium diclofenac‐loaded microspheres into a calcium hydroxide paste enhances antibiofilm activity while maintaining physicochemical properties and biocompatibility. Calcium hydroxide paste, calcium hydroxide combined with sodium diclofenac, and calcium hydroxide containing sodium diclofenac ...
João Vitor Oliveira de Amorim +6 more
wiley +1 more source
Subcellular localization of the P2X4 receptor in sensory hair cells of Wistar rat cochlea. [PDF]
Huang Z +7 more
europepmc +1 more source
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
Comparative Efficacy of Pioglitazone, Saroglitazar, and Silymarin on Biochemical and Histopathological Hepatic Outcomes in a Wistar Rat Model of Non-alcoholic Fatty Liver Disease and Their Correlation With Insulin Sensitivity. [PDF]
Jain I, Nath R, Kumar M, Pal R, Dixit R.
europepmc +1 more source
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley +1 more source
Two-Stage Microwave Hyperthermia Using Magnetic Nanoparticles for Optimal Chemotherapy Activation in Liver Cancer: Concept and Preliminary Tests on Wistar Rat Model. [PDF]
Schreiner OD +3 more
europepmc +1 more source

