Results 261 to 270 of about 237,978 (340)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Anti-Obesity Effects Evaluation of a Blackcurrant Leaf Standardized Hydro-Alcoholic Extract in Wistar Rat Subjected to a High-Fat Diet. [PDF]

open access: yesBiology (Basel)
Bréger G   +7 more
europepmc   +1 more source

Resolution of inflammation in pulmonary arterial hypertension, the influence of sex—An IUPHAR immunopharmacology committee review

open access: yesBritish Journal of Pharmacology, EarlyView.
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy   +5 more
wiley   +1 more source

The healing effect of nano emulsified Plantago major L extract on oral wounds in a wistar rat model. [PDF]

open access: yesBMC Complement Med Ther
Jahanimoghadam F   +5 more
europepmc   +1 more source

Odanacatib Coating Supports Osseointegration of Implants: A Preclinical Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Introduction Odanacatib (ODN), a cathepsin K inhibitor, is a drug that reduces bone resorption while preserving bone formation. ODN was initially developed for the treatment of postmenopausal osteoporosis, but further development as a systemic medication has been discontinued.
Natália dos Santos Sanches   +10 more
wiley   +1 more source

Effects of methotrexate on Wnt/β‐catenin signaling and glial activation in temporomandibular joint arthritis in rats

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract Rheumatoid arthritis is a chronic autoimmune disease that can affect the temporomandibular joint (TMJ) and cause pain. Methotrexate is widely used to control disease progression, but its effects on pain mechanisms are not fully understood. This study evaluated the antinociceptive effects of methotrexate on pain behavior, Wnt/β‐catenin pathway ...
Ana Carolina de Figueiredo Costa   +6 more
wiley   +1 more source

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