Results 111 to 120 of about 364,482 (359)

Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]

open access: yes, 2014
Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Ahima   +40 more
core   +1 more source

Tooth eruption status and bite force determine dental microwear texture gradients in albino rats (Rattus norvegicus forma domestica)

open access: yesThe Anatomical Record, EarlyView.
Abstract Dental microwear texture analysis (DMTA) is widely applied for inferring diet in vertebrates. Besides diet and ingesta properties, factors like wear stage and bite force may affect microwear formation, potentially leading to tooth position‐specific microwear patterns.
Daniela E. Winkler   +2 more
wiley   +1 more source

Avaliação da lesão isquêmica normotérmica do fígado: papel da oclusão do ducto biliar principal e da N-acetilcisteína

open access: yesRevista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Estudar o efeito da N-acetilcisteína (NAC) na isquemia hepática. MÉTODO: Trinta e oito ratos machos EPM-1 Wistar foram distribuídos em quatro grupos.
Susi Heliene Lauz Medeiros   +5 more
doaj   +1 more source

NOP Receptor Agonist Ro 64-6198 Decreases Escalation of Cocaine Self-Administration in Rats Genetically Selected for Alcohol Preference

open access: yesFrontiers in Psychiatry, 2019
Cocaine dependence is a psychiatric condition for which effective medications are still lacking. Published data indicate that an increase in nociceptin/orphanin FQ (N/OFQ) transmission by NOP receptor activation attenuates cocaine-induced place ...
Hongwu Li   +7 more
doaj   +1 more source

Contribution of Organic Anion Transporter 3 in Delayed Elimination of Methotrexate by Concomitant Administration of Febuxostat

open access: yesBiopharmaceutics &Drug Disposition, EarlyView.
Coadministration of the xanthine oxidase inhibitor, febuxostat, delayed elimination of methotrexate, at least in part, by noncompetitive inhibition of human organic anion transporter 3‐mediated methotrexate transport at clinical concentrations. The findings of this study provide novel information on drug interactions associated with febuxostat ...
Kenji Ikemura   +3 more
wiley   +1 more source

Prevention of Protein Glycation by Natural Compounds [PDF]

open access: yes, 2015
Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz   +1 more
core   +2 more sources

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Effect of Wheat/Cassava Composite Bread on Liver Architecture of Wistar Rat

open access: yesJournal of Pure and Applied Microbiology, 2018
This study reports the effect of different levels of wheat/cassava composite flour on liver architecture of wistar rat. The cassava variety- TMS 98/419 and Twenty (20) male wistar rats were used for the study.
M.O. Odo   +3 more
doaj   +1 more source

The Mortality and Body Weight Response of Male Wistar Rats in the Lethal X-ray Dose Range [PDF]

open access: bronze, 1969
S Tsuchihashi   +4 more
openalex   +1 more source

Discovery of the Postcoital Contraceptive Effect of Rhus pentaphylla in a Study of Acute, Subchronic, and Neurodevelopmental Toxicity of Ethanolic Leaf Extract

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT In the present study, the acute, subchronic, and neurodevelopmental toxicity of Rhus pentaphylla, a Moroccan medicinal plant, was investigated in Swiss albino mice. HPLC analysis showed the presence of phenolic compounds with rutin as the principal component.
Fatimazahra Agouram   +4 more
wiley   +1 more source

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