Results 131 to 140 of about 328,483 (267)

Experimental Diabetic Retinopathy in Wistar Rats Induced by Streptozotocin: A Window into Retinal Disease Progression. [PDF]

Int J Mol Sci
Barba-Gallardo LF, Ávila-Blanco ME, Ventura-Juárez J, Muñoz-Ortega MH, Murillo-Ruíz RC, Rivera-Delgadillo M, Díaz-Rubio JL, Casillas-Casillas E, Salas-Hernández LH, Guerra-Ávila PL.   +9 more
europepmc   +1 more source

Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease

Neuroprotection, EarlyView.
In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong, Andrew Octavian Sasmita, Rhun Yian Koh, Anna Pick Kiong Ling   +3 more
wiley   +1 more source

Supraphysiological Doses of Vitamin A Promote Changes in Hippocampal Oscillation Bands and Cardiac Activity in Wistar Rats. [PDF]

ACS Omega
Hartcopff PFP, Lins A, de Araujo DB, Barbosa GB, de Souza LV, Hamoy MKO, Eiró-Quirino L, de Lima SMA, Muto NA, Lopes DCF, Hamoy M.   +10 more
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Photobiomodulation and Sericin in the Treatment of Second-Degree Burns Induced in Wistar Rats. [PDF]

Wound Repair Regen
de Araújo Pradal L, Dahleh MMM, Prigol M, Guerra GP, da Rocha Paiva C, Schnaufer TC, de Fátima Chasko Ribeiro L, Costa RM, Bertolini GRF.   +8 more
europepmc   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Acute and Subacute Oral Toxicity Evaluation of <i>Baccaurea motleyana</i> Fruit Extract in Wistar Rats. [PDF]

Food Sci Nutr
Hasan MM, Bhuyan EA, Ekram MEH, Proma NM, Hossain MK.   +4 more
europepmc   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Brief results of heterotopic xenotransplantation of meningioma into the peritoneum of Wistar rats: an experimental study. [PDF]

Braz J Med Biol Res
Silva Junior LFMD, Santos MJSD, Carmo AOD, Silva ROL, Campos MAG, Silva GEB, Santos OJD, Salgado Filho N.   +7 more
europepmc   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source