Results 141 to 150 of about 328,483 (267)

Prenatal Developmental Toxicity of ARVIDEX® Herbal Medicine in Albino Wistar Rats. [PDF]

Cureus
Engeu Ogwang P, Joshua K, Katende P, Arisinga TR, Kyomugisha S, Neeza T, Terkimbi SD, Mekuriya Yadesa T, Mwandah DC.   +8 more
europepmc   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan, Candace L. Doepker, Gregory P. Brorby   +2 more
wiley   +1 more source

Melatonin mitigates dichlorvos-induced derangements in the testes and epididymis of male Wistar rats. [PDF]

Anim Reprod
Ajani OS, Samuel ES.
europepmc   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Analgesic and Anti-Inflammatory Activity of Ambroxol in the Treatment of Endometriosis: An Experimental Study in Wistar Rats. [PDF]

Pharmaceuticals (Basel)
Frota GM, Santos WGB, Tenório-Meireles J, Silva ER, Reis ATF, Santos RAP, Sousa LR, Carvalho RAF, Sousa JCS, Sousa EM, Lima RA, Carvalho RC, Andrade MS, Garcia JBS, Cartágenes MDSS.   +14 more
europepmc   +1 more source

Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions

Sensory Neuroscience, EarlyView.
ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang, Yu Xiao, Jiaxin Liu, Wen Jiang, Weiwei Shi, Hanbing Zhang, Xiaolong Fu, Yunhao Wu   +7 more
wiley   +1 more source

Preliminary insights into intratesticular and intraepididymal administration of eugenol: histological alterations and impact on sperm motility in Wistar rats. [PDF]

Anim Reprod
Carvalho RPR, Ribeiro IM, Ramirez-Lopez C, da Silva TB, de Sousa AFR, de Azevedo Viana AG, de Medeiros V, Trindade ACM, Ferreira TRM, Ervilha LOG, Machado-Neves M.   +10 more
europepmc   +1 more source

In Vitro Reconstruction of Axonal Heat Sensing with a Photothermal Nerve‐on‐a‐Chip

Small, EarlyView.
A photothermal nerve‐on‐a‐chip platform is presented that enables precise, localized heating of sensory axons with simultaneous electrical recording. The system reveals millisecond‐scale dynamics of heat‐evoked neural activity and provides a new approach to study how temperature‐dependent ion channel behavior is translated into axonal firing.
Koji Sakai, Yujiro Tanaka, Riku Takahashi, Toichiro Goto, Yosuke Mizuno, Taiki Otomo, Aya Tanaka   +6 more
wiley   +1 more source

Cardiotoxic effects of pantoprazole in Wistar rats submitted to cardiac ischemia and reperfusion. [PDF]

Rev Assoc Med Bras (1992)
Santos ACD, Silva CMC, Araújo EA, Sassi LO, Caixeta A, Taha MO, Pires-Oliveira M, Caricati-Neto A, Lopes RD, Tallo FS, Menezes-Rodrigues FS.   +10 more
europepmc   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source