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Toxicology Reference Data for the Wistar Rat
1982Sixty-six observations on Wistar rats, including body and organ weights, biochemistry, hematology, and urinalysis have been compiled over a period of 16 years. A statistical analysis of these observations involved 3,400 Wistar rats that served as controls in toxicity studies.
P J, Lewi, R P, Marsboom
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Tumor-Induced Anorexia in the Wistar Rat
Science, 1981The transplantable Leydig cell tumor of Wistar rats, LTW(m), caused decreased food consumption and weight loss in the host within 2 weeks of implantation. The tumor was small, did not metastasize, and did not affect several parameters of biochemical function.
J P, Mordes, A A, Rossini
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Teratogenicity of ionic cadmium in the Wistar rat
Archives of Toxicology, 1987In rats of the present (re-derived) Wistar-Porton strain that are dosed either intravenously (i.v.), or intraperitoneally (i.p.) with Cd (1.25 mg/kg body weight) on day 12 of gestation (gd 12), foetal uptake of Cd is at least 6-fold greater than that reported in an earlier study (Webb and Samarawickrama 1981).
D, Holt, M, Webb
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Lymphoproliferative lesions in BB Wistar rats
Metabolism, 1983Fifteen percent of long-term diabetic BB Wistar rats developed abdominal B cell lymphoproliferative lesions which ranged from minute mesenteric aggregates of plasma cells and lymphocytes to malignant lymphoma with features of immunoblastic sarcoma or plasma-cell lymphoma.
T A, Seemayer +3 more
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Polymorphism in Diazepam Metabolism in Wistar Rats
Journal of Pharmaceutical Sciences, 2004We observed variations in the metabolism of diazepam in Wistar rats. We studied these variations carefully, and found that the variations are dimorphic and about 17% of male rats of Wistar strain we examined showed two times higher diazepam metabolic activities in their liver microsomes than the rest of animals at the substrate concentrations less than
Konomu, Saito +5 more
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Teratogenic Effect of Semicarbazide in Wistar Rats
Biology of the Neonate, 2009Five groups of pregnant Wistar rats were injected intraperitoneally with a single dose of semicarbazide (SC) on day 5, 7, 10, 13, or 15 of gestation. The lots in each group received either 50, 75, 100 or 150 mg/kg SC. A sixth group received 17 mg/kg of the drug during the entire course of pregnancy.
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Sleeve Gastrectomy Model in Wistar Rats
Obesity Surgery, 2007Sleeve gastrectomy (SG) has been used for the surgical treatment of morbid obesity, as a first step or as a definitive treatment. The objective of this pilot study was to establish an animal model for SG in Wistar rats.12 male Wistar rats were operated on.
João, de Bona Castelan +6 more
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Hyponeophagia in Wistar Kyoto (WKY) Rats
Physiology & Behavior, 1994Unconditioned suppression of feeding due to novelty (hyponeophagia) was studied in Wistar Kyoto (WKY), Lewis, Fischer 344, and Wistar rats. Fasted rats were given access to food either in home cages (controls) or to a single pellet fixed to the middle of a novel open field environment (experimental).
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Lipids, 1976
AbstractThe bile acid pool was found to be ca. 50 μmoles/100 g body wt in male and female rats maintained on standard laboratory chow and ca. 30 μmoles/100 g body wt in those maintained on a standard semisynthetic diet. The distribution of bile acids within the pool was similar in plasma, liver, and intestinal tract, except for a higher concentration ...
M M, Fisher, G, Kakis, I M, Yousef
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AbstractThe bile acid pool was found to be ca. 50 μmoles/100 g body wt in male and female rats maintained on standard laboratory chow and ca. 30 μmoles/100 g body wt in those maintained on a standard semisynthetic diet. The distribution of bile acids within the pool was similar in plasma, liver, and intestinal tract, except for a higher concentration ...
M M, Fisher, G, Kakis, I M, Yousef
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