Results 41 to 50 of about 1,362,016 (348)

Dopamine D3 Receptor Antagonism Reverses the Escalation of Oxycodone Self-administration and Decreases Withdrawal-Induced Hyperalgesia and Irritability-Like Behavior in Oxycodone-Dependent Heterogeneous Stock Rats

Frontiers in Behavioral Neuroscience, 2020
Prescription opioids, such as oxycodone, are highly effective analgesics for clinical pain management, but approximately 25% of patients who are prescribed opioids misuse them, and 5%–10% develop an opioid use disorder (OUD).
Giordano de Guglielmo, Marsida Kallupi, Sharona Sedighim, Amy H. Newman, Olivier George   +4 more
doaj   +1 more source

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes

Frontiers in Pharmacology, 2018
Ibogaine may be effective for transitioning opioid and cocaine dependent individuals to sobriety. American and European self-help groups provided public testimonials that ibogaine alleviated drug craving and opioid withdrawal symptoms after only a single
Deborah C. Mash, Deborah C. Mash, Linda Duque, Bryan Page, Kathleen Allen-Ferdinand   +4 more
doaj   +1 more source

Is there a potential of misuse for venlafaxine and bupropion? [PDF]

, 2018
© 2018 Schifano and Chiappini. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the ...
Anderson, Augustin, Baker, Baribeau, Bolden-Watson, Campagne, Carvalho, Chiappini, Chiappini, Chouinard, Cosci, Cutler, Deluca, Evans, Fava, Fava, Fountain, Francesconi, Groot, Harvey, Harvey, Hill, Hilliard, Holland, Hopper, Hu, Kantor, Kelly, Khurshid, Kim, Koga, Kotzalidis, Langguth, Lewin, Llorca, Maj, McCormick, Muth, Nelson, Orsolini, Parker, Phillips, Quaglio, Redrobe, Reeves, Renoir, Rettew, Rudolph, Sabljić, Schifano, Schifano, Shang, Shenouda, Sir, Stahl, Stahl, Stahl, Stall, Stassinos, Taylor, Vento, Weikop, Welsh, Wilson, Yoon   +64 more
core   +2 more sources

Viscous Withdrawal of Miscible Liquid Layers

, 2007
In viscous withdrawal, a converging flow imposed in an upper layer of viscous liquid entrains liquid from a lower, stably stratified layer. Using the idea that a thin tendril is entrained by a local straining flow, we propose a scaling law for the volume
G. I. Taylor, Laura E. Schmidt, Wendy W. Zhang   +2 more
core   +1 more source

Neonatal Drug Withdrawal [PDF]

Pediatrics, 2012
Maternal use of certain drugs during pregnancy can result in transient neonatal signs consistent with withdrawal or acute toxicity or cause sustained signs consistent with a lasting drug effect. In addition, hospitalized infants who are treated with opioids or benzodiazepines to provide analgesia or sedation may be at risk for manifesting signs of ...
Lu Ann Papile, Ian M. Paul, John N. van den Anker, Tonse N.K. Raju, Anne Zajicek, Kasper S. Wang, Janet D. Cragan, Hari Cheryl Sachs, Wanda D. Barfield, Mary A. Hegenbarth, David H. Adamkin, Waldemar A. Carlo, Praveen Kumar, Mark L. Hudak, Vinod K. Bhutani, Richard A. Polin, Robert E. Shaddy, Wayne R. Snodgrass, Raymond J. Koteras, Jill E. Baley, John J. Alexander, George Macones, Kathleen A. Neville, Ann L Jefferies, Mark Del Monte, Michael J Rieder, Jeffrey L. Galinkin, James J. Cummings, Matthew Knight, Kristi L. Watterberg, Rosalie O. Mainous, Adelaide Robb, Jim Couto, William H. Barth, George P. Giacoia, Daniel A.C. Frattarelli, Thomas P. Green, Rosemarie C. Tan, Nancy C. Chescheir   +38 more
openaire   +5 more sources

Brain systems in cocaine abstinence-induced anxiety-like behavior in rodents: A review

Addiction Neuroscience, 2022
Cocaine use disorder (CUD) is a significant public health issue that generates substantial personal, familial, and economic burdens. Still, there are no FDA-approved pharmacotherapies for CUD.
Britton R. Barbee, Shannon L. Gourley
doaj  

Anti-psychotics: To withdraw or not to withdraw?

European Psychiatry, 2017
IntroductionAnti-psychotics constitute a class of psychotropic drugs used for the treatment and prophylaxis of several disorders, including schizophrenia, bipolar disorder and psychotic depression. Frequently, clinicians are asked by their patients to withdraw this medication. In some cases, that may be related to notable side effects.
C. Ferreira, C. Oliveira, M.J. Avelino, S. Alves   +3 more
openaire   +2 more sources

Glucocorticoid Withdrawal in Lupus Nephritis: A Study Protocol and Literature Review

Journal of Clinical Rheumatology and Immunology, 2020
Although glucocorticoids (GCs) are the cornerstone for the treatment for systemic lupus erythematosus (SLE), they are associated with a number of adverse effects.
Natalia Chu Oi Ciang, Chi Chiu Mok
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Assessing the 2004-2018 fentanyl misusing issues reported to an international range of adverse reporting systems [PDF]

, 2019
© 2019 Schifano, Chiappini, Corkery and Guirguis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania, Corkery, John, Guirguis, Amira, Schifano, Fabrizio   +3 more
core   +3 more sources