Results 231 to 240 of about 2,510,208 (357)

Real‐world use of adjunctive perampanel for focal‐onset seizures in Italy: A mirroring clinical practice study of perampanel in adults and adolescents (AMPA)

Epilepsia Open, EarlyView.
Abstract Objective The AMPA study (Study 501; NCT04257604) was a multicenter, prospective, 12‐month observational study in Italy that evaluated the effectiveness and safety of adjunctive perampanel in patients with focal‐onset seizures (FOS), with or without focal to bilateral tonic–clonic seizures (FBTCS).
Alfredo D'Aniello, Anna Teresa Giallonardo, Paolo Tinuper, Oriano Mecarelli, Umberto Aguglia, Giovanni Assenza, Antonio Gambardella, Maria Paola Canevini, Renato Scifo, Stefano Meletti, Valentina De Giorgis, Enrica Bonanni, Roberto Michelucci, Caterina Cerminara, Antonino Romeo, Federico Vigevano, Francesca Felicia Operto, Luciana Tramacere, Giancarlo Di Gennaro, Alfonso Iudice on behalf of the AMPA Study group, Leock Y. Ngo, Anna Patten, Anna Lisa Gentile, Andrea Pecori, Samantha Goldman   +24 more
wiley   +1 more source

A Review Study on the Effect of Iranian Herbal Medicines on Opioid Withdrawal Syndrome

Journal of Evidence-Based Complementary & Alternative Medicine, 2015
M. Ebrahimie, M. Bahmani, H. Shirzad, M. Rafieian-kopaei, K. Saki   +4 more
semanticscholar   +1 more source

Is highly purified cannabidiol a treatment opportunity for drug‐resistant epilepsy in subjects with typical Rett syndrome and CDKL5 deficiency disorder?

Epilepsia Open, EarlyView.
Abstract Objective This study aimed to evaluate the efficacy and safety of adjunctive, highly purified Cannabidiol (Epidiolex®) in individuals with drug‐resistant epilepsy (DRE) due to genetically determined typical Rett Syndrome (RTT) and CDKL5 Deficiency Disorder (CDD). Methods We recruited subjects with genetically confirmed typical RTT and CDD with
Aglaia Vignoli, Giulia Prato, Enrico Alfei, Irene Bagnasco, Alberto Danieli, Massimiliano Celario, Jacopo Favaro, Sara Matricardi, Francesca Felicia Operto, Alessandro Orsini, Davide Paolo Bernasconi, Nicola Pietrafusa, Emilia Ricci, Luca Manfredini, Giulia Balletto, Paolo Bonanni, Maria Paola Canevini, Valentina De Giorgis, Lino Nobili, Stefano Sartori, Miriam Nella Savini, Ilaria Viganò, Nicola Specchio   +22 more
wiley   +1 more source

SCN1A gain of function effects in Dravet syndrome: Insights into clinical phenotypes and therapeutic implications

Epilepsia Open, EarlyView.
Abstract A large number of cases with Dravet syndrome (DS) has been attributed to SCN1A loss of function (LOF), whereas SCN1A gain‐of‐function (GOF) causes early infantile developmental and epileptic encephalopathy (EIDEE) and familial hemiplegic migraine 3.
Yoko Kobayashi Takahashi, Kenshiro Tabata, Shimpei Baba, Eri Takeshita, Noriko Sumitomo, Yuko Shimizu‐Motohashi, Takashi Saito, Eiji Nakagawa, Atsushi Ishii, Shinichi Hirose, Mitsuhiro Kato, Naomichi Matsumoto, Hirofumi Komaki, Ken Inoue   +13 more
wiley   +1 more source

Anticonvulsants for the Treatment of Alcohol Withdrawal Syndrome and Alcohol Use Disorders

CNS Drugs, 2015
C. Hammond, M. Niciu, Shannon Drew, A. Arias   +3 more
semanticscholar   +1 more source

The upside of epilepsy: Theories of an evolutionary paradox

Epilepsia Open, EarlyView.
Abstract The persistence of common, heritable conditions, like epilepsy, that are associated with reduced reproductive fitness is an evolutionary paradox. Endogenous analgesic, anti‐depressant, and inflammatory mechanisms able to repair compromised functions can offer advantages in unexpected crises.
Alyssa Ailion, Christoph Helmstaedter, Annamaria Vezzani, Matthias J. Koepp   +3 more
wiley   +1 more source

Food Addiction in Individuals With Overweight and Obesity Undergoing a 12‐Week Long Tailored mHealth Weight Loss Intervention

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Former studies indicated worse outcome for individuals with food addiction (FA) when participating in weight loss programs. Yet, the results may have been influenced by comorbid eating disorders and insufficient consideration of psychological aspects associated with FA.
Magdalena Pape, Stephan Herpertz, Tanja Färber, Caroline Seiferth, Natalie Schoemann, Jörg Wolstein, Sabine Steins‐Loeber   +6 more
wiley   +1 more source

Characterization of alcohol-related seizures in withdrawal syndrome. [PDF]

Epilepsia Open
Kádár BK, Gajdics J, Pribék IK, Andó B, Lázár BA.   +4 more
europepmc   +1 more source

Food for Thought: A Systematic Review and Meta‐Analysis on the Effects of Ultra‐Processed Foods on Cognition in Children and Adolescents

Food Frontiers, EarlyView.
Across 35 studies, this systematic review and meta‐analysis explored the link between ultra‐processed foods (UPFs) and cognition. For children, higher consumption of UPFs was associated with poorer attention, executive functioning, fluid intelligence, and language; for adolescents, higher UPF consumption was associated with poorer executive functioning,
Lan Nguyen, Jared Walters, Bernadette Spies, Amelia Coppus, Jenaya Massie, Thamiris Penteado Bertonha   +5 more
wiley   +1 more source

Pharmacokinetic Modeling and Model-Based Hypothesis Generation for Dose Optimization of Clonidine in Neonates With Neonatal Opioid Withdrawal Syndrome. [PDF]

Clin Pharmacol Ther
Tang F, Ng CM, Horn J, Bada HS, Leggas M.   +4 more
europepmc   +1 more source