Results 51 to 60 of about 6,857,827 (289)

Process of life-sustaining treatment in general hospital: withholding and withdrawing

Revista de Bioética y Derecho, 2011
Introducción: La limitación del esfuerzo terapéutico (LET) es una práctica frecuente en los Servicios de Medicina Intensiva (SMI) que asocia a una mortalidad elevada.
Lorenzo Socias Crespí, Rosa Poyo-Guerrero Lahoz   +1 more
doaj   +1 more source

Comparison of the end-of-life decisions of patients with hospital-acquired pneumonia after the enforcement of the life-sustaining treatment decision act in Korea

BMC Medical Ethics, 2023
Background Although the Life-Sustaining Treatment (LST) Decision Act was enforced in 2018 in Korea, data on whether it is well established in actual clinical settings are limited.
Ae-Rin Baek, Sang-Bum Hong, Soohyun Bae, Hye Kyeong Park, Changhwan Kim, Hyun-Kyung Lee, Woo Hyun Cho, Jin Hyoung Kim, Youjin Chang, Heung Bum Lee, Hyun-Il Gil, Beomsu Shin, Kwang Ha Yoo, Jae Young Moon, Jee Youn Oh, Kyung Hoon Min, Kyeongman Jeon, Moon Seong Baek, and the Korean HAP/VAP Study Group   +18 more
doaj   +1 more source

“We Absolutely Had the Impression That It Was Our Decision”—A Qualitative Study with Parents of Critically Ill Infants Who Participated in End-of-Life Decision Making

Children, 2022
Background: Guidelines recommend shared decision making (SDM) between neonatologists and parents when a decision has to be made about the continuation of life-sustaining treatment (LST).
Maria Florentine Beyer, Katja Kuehlmeyer, Pezi Mang, Andreas W. Flemmer, Monika Führer, Georg Marckmann, Mirjam de Vos, Esther Sabine Schouten   +7 more
doaj   +1 more source

Universal Battery Capacity Degradation Forecasting Driven by Foundation Models Across Diverse Chemistries and Conditions

Advanced Science, EarlyView.
A unified time‐series forecasting framework learns transferable battery capacity‐degradation patterns from 20 heterogeneous datasets spanning chemistries, formats, temperatures, and cycling conditions. A single model delivers competitive predictions on both known and previously unseen datasets, while physics‐guided representation learning improves ...
Joey Chan, Huan Wang, Zhen Chen, Haoyu Pan, Wei Wu, Zirong Wang, Ershun Pan, Min Xie, Lifeng Xi   +8 more
wiley   +1 more source

Predicting Single‐Cell Perturbation Responses Across Biological Contexts With a Deep Generative Model Integrating Optimal Transport

Advanced Science, EarlyView.
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang, Ziqi Liu, Zhengqian Zhang, Yikun Cao, Junjun Ren, Peng Cheng, Jingjing Tian, Lingyun Xie, Xin Lu, Zhanwei Du, Yongzhuang Liu   +10 more
wiley   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

Advanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri, A. Mangiarotti, C. N. Z. Schmitt, R. Dimova   +3 more
wiley   +1 more source

Physicians’ experiences and perceptions about withholding and withdrawal life-sustaining treatment in Chiang Mai University Hospital: a cross-sectional study

BMC Palliative Care
Background Withholding or withdrawing life-sustaining treatment in end-of-life patients is a challenging ethical issue faced by physicians. Understanding physicians’ experiences and factors influencing their decisions can lead to improvement in end-of ...
Nattanit Ketchaikosol, Kanokporn Pinyopornpanish, Chaisiri Angkurawaranon, Nisachol Dejkriengkraikul, Lalita Chutarattanakul   +4 more
doaj   +1 more source

End-of-Life Practices in an Intensive Care Unit of a Private Hospital in Mexico

Palliative Medicine Reports
Background: Many factors, such as religion, geography, and customs, influence end-of-life practices. This variability exists even between different physicians.
Roberto Carlos Miranda-Ackerman, Paulina Ruiz-Ochoa, Daniela López-Ramírez, Juan Fernando Quevedo-Barrientos, Mariana Plascencia-Rendón, José Luis Landeros-Torres, Karen Fernanda Astorga-Cervantes, Alejandra González-Uribe, Ana Olivia Cortes-Flores, Carlos José Zuloaga-Fernández- del-Valle, Gilberto Morgan-Villela, Francisco José Barbosa-Camacho, Clotilde Fuentes-Orozco, Irma Valeria Brancaccio-Pérez, Alejandro González-Ojeda   +14 more
doaj   +1 more source

Attitudes and behaviors of Japanese physicians concerning withholding and withdrawal of life-sustaining treatment for end-of-life patients: results from an Internet survey

BMC Medical Ethics, 2007
Background Evidence concerning how Japanese physicians think and behave in specific clinical situations that involve withholding or withdrawal of medical interventions for end-of-life or frail elderly patients is yet insufficient.
Bito Seiji, Asai Atsushi
doaj   +1 more source