Results 51 to 60 of about 7,359,221 (290)

Assisted dying is not the same as withdrawing or withholding life sustaining treatment – Letter on Costello and Fazzini

Dear Editor, We read with interest, the publication by Costello and Fazzini,1 which reports a scoping review examining the attitudes and practices of intensive care unit (ICU) clinicians in relation to assisted dying. Assisted dying emphasises choice and
Hewitt, Jayne, Bonner, Ann, Bloomer, Melissa J   +2 more
core   +2 more sources

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

Advanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri, A. Mangiarotti, C. N. Z. Schmitt, R. Dimova   +3 more
wiley   +1 more source

Withholding treatment in infancy [PDF]

BMJ, 1981
Terry, Hamblin, K P, Roche, I M, Jessiman   +2 more
  +10 more sources

Hospital and Temporal Variations in Limitations of Care Among Hospitalized Patients with COVID-19: A VIRUS Registry Retrospective Cohort Study

Palliative Medicine Reports
Introduction: Life-support limits (i.e., code status), the first step in the continuum of palliation and end-of-life (EoL) care, stem from decisions made by patients and their providers to align care near the EoL with patients’ wishes.
Nathan Mesfin, Nitesh Kumar Jain, Anwar Khedr, Hisham Mushtaq, Abbas B. Jama, Noura Attallah, Esraa Hassan, Benjamin Langworthy, Nicholas Ingraham, Juan Pablo Domecq Garces, Thoyaja Koritala, Donna Lee Armaignac, Nicholas Eugene Perkins, Katherine Belden, Vishakha Kumar, Karen Boman, Devang K. Sanghavi, Vikas Bansal, Rahul Kashyap, Rodrigo Cartin-Ceba, Abigail La Nou, Allan J. Walkey, R. Adams Dudley, Syed Anjum Khan   +23 more
doaj   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

End-of-Life Practices in an Intensive Care Unit of a Private Hospital in Mexico

Palliative Medicine Reports
Background: Many factors, such as religion, geography, and customs, influence end-of-life practices. This variability exists even between different physicians.
Roberto Carlos Miranda-Ackerman, Paulina Ruiz-Ochoa, Daniela López-Ramírez, Juan Fernando Quevedo-Barrientos, Mariana Plascencia-Rendón, José Luis Landeros-Torres, Karen Fernanda Astorga-Cervantes, Alejandra González-Uribe, Ana Olivia Cortes-Flores, Carlos José Zuloaga-Fernández- del-Valle, Gilberto Morgan-Villela, Francisco José Barbosa-Camacho, Clotilde Fuentes-Orozco, Irma Valeria Brancaccio-Pérez, Alejandro González-Ojeda   +14 more
doaj   +1 more source

Respective impact of no escalation of treatment, withholding and withdrawal of life-sustaining treatment on ICU patients’ prognosis: a multicenter study of the Outcomerea Research Group

, 2015
International audienceTo assess the prevalence of decisions to forgo life-sustaining treatment (DFLST), the patients characteristics, and to estimate the impact of DFLST stages on mortality.METHODS:Observational study of a prospective database between ...
Lautrette, Alexandre, Jamali, Samir, Bertrand, Pierre-Marie, Goldgran-Toledano, Dany, Darmon, Michaël, Ruckly, Stéphane, Souweine, Bertrand, Bertrand, Bertrand, Argaud, Laurent, Dumenil, Anne-Sylvie, Timsit, Jean-François, Garrouste-Orgeas, Maïté, Lemiale, Virginie, Schwebel, Carole, Mourvillier, Bruno, Laurent, Virginie   +15 more
core   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Accelerated Discovery of Earth‐Abundant Oxygen Evolution Catalysts Through Surface‐Informed Active Learning

Advanced Science, EarlyView.
A surface‐informed active learning framework integrated with density functional theory enables resource efficient screening of the NiCoFe ternary composition space. Experimental validation identifies Ni55Co10Fe35 as the optimal composition, exhibiting favorable oxygen evolution reaction kinetics.
Hayun Jeon, Minhee Park, Won Bo Lee, Seyoung Park, YongJoo Kim, Sungwook Mhin   +5 more
wiley   +1 more source

Probe‐Free, Primer‐Programmed Amplicon Encoding Enables Nanopore‐Based Multiplex Detection With Deep Learning Decoding

Advanced Science, EarlyView.
Primer‐programmed amplicon encoding enables reporter‐probe‐free multiplex nucleic acid identification using glass nanopore sensing and deep neural network decoding. ABSTRACT Single‐reaction multiplex nucleic acid testing (NATs) must both co‐amplify multiple targets and distinguish the resulting amplicons within the product mixture.
Md. Ahasan Ahamed, Muhammad Asad Ullah Khalid, Wahid Uz Zaman, Anthony J. Politza, Weihua Guan   +4 more
wiley   +1 more source