Results 61 to 70 of about 39,136 (290)

Assisted dying is not the same as withdrawing or withholding life sustaining treatment – Letter on Costello and Fazzini [PDF]

Dear Editor, We read with interest, the publication by Costello and Fazzini,1 which reports a scoping review examining the attitudes and practices of intensive care unit (ICU) clinicians in relation to assisted dying. Assisted dying emphasises choice and
Hewitt, Jayne, Bonner, Ann, Bloomer, Melissa J   +2 more
core   +1 more source

Affective dimensions in the information behavior of forcibly displaced people: A literature review. An Annual Review of Information Science and Technology (ARIST) paper

Journal of the Association for Information Science and Technology, EarlyView.
Abstract This review analyzed 241 scholarly articles published between 2010 and 2025 in information science venues to examine how affect shapes refugees' information behavior during forced migration and to identify additional contextual factors. It identifies seven affective dimensions: anxiety, shame and stigma, grief and loss, frustration, (mis)trust,
Maja Krtalić, Lilach Alon
wiley   +1 more source

Examining the Validity and Reliability of Evaluation in Ayres Sensory Integration Data Collected With Autistic Children: A Rasch Analysis

Autism Research, EarlyView.
ABSTRACT Performance‐based assessments of sensory function provide essential insights into sensory integration challenges in autistic children and provide objective, standardized measurement data that can be used to tailor targeted interventions. We sought to evaluate the validity and reliability of data collected using the Evaluation in Ayres Sensory ...
Patricia Grady‐Dominguez, Anita C. Bundy, Zoe Mailloux, Roseann C. Schaaf   +3 more
wiley   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

British Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Laura M. Dember, Todd A. Miano, Tat‐Thang Vo, Allison W. Willis, Charles E. Leonard   +8 more
wiley   +1 more source

Treatment-limiting decisions in patients with severe traumatic brain injury in a Norwegian regional trauma center

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2017
Background Treatment-limiting decisions (TLD) for severe traumatic brain injury (sTBI) have been sparsely studied. This study determine prevalence, main reason for, categories and timing of TLDs in a Norwegian regional trauma setting.
Annette Robertsen, Reidun Førde, Nils Oddvar Skaga, Eirik Helseth   +3 more
doaj   +1 more source

Malaria Rapid Testing by Community Health Workers is Effective and Safe for Targeting Malaria Treatment: Randomised Cross-over Trial in Tanzania. [PDF]

, 2011
Early diagnosis and prompt, effective treatment of uncomplicated malaria is critical to prevent severe disease, death and malaria transmission. We assessed the impact of rapid malaria diagnostic tests (RDTs) by community health workers (CHWs) on ...
Petzold, M.G, Ka¨ llander, K., Max G. Petzold, Gustafsson, Lars L, Marian Warsame, Massele Amos, Källander, K,, Lars L Gustafsson, Gustafsson Lars L., Mubi, M., Massele, Amos, Max G Petzold, Premji, Z., Tomson, G, Björkman, Anders, Marycelina Mubi, Amos Massele, Premji, Zul, Ngasala Billy, Maganga, G., Karin Källander, Maganga, G,, Mubi, Marycelina, Anders Björkman, Warsame, M,, Warsame, M., Ngasala, Billy, Petzold Max G., Maganga, Gloria, Kallander, K., Björkman Anders, Zul Premji, Mårtensson, Andreas, Tomson, G., Martensson, A., Bjorkman, A., Ngasala, B., Mårtensson, A,, Petzold, Max G, Ngasala, B,, Göran Tomson, Tomson, Göran, Tomson Göran, Massele, A., Mårtensson Andreas, Lars L. Gustafsson, Massele, A,, Petzold, M.G., Bjo¨rkman, A., Janson, A,, Petzold, M.G,, Premji Zul, Maganga Gloria, Janson, A., Andreas Mårtensson, Gloria Maganga, Warsame, Marian, Gustafsson, L.L, Källander, Karin, Warsame Marian, Källander Karin, Mub, M., Janson Annika, Billy Ngasala, Janson, Annika, Mubi Marycelina, Gustafsson, L.L., Gustafsson, L.L,, Ma°rtensson, A., Annika Janson   +69 more
core   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

Physicians’ experiences and perceptions about withholding and withdrawal life-sustaining treatment in Chiang Mai University Hospital: a cross-sectional study

BMC Palliative Care
Background Withholding or withdrawing life-sustaining treatment in end-of-life patients is a challenging ethical issue faced by physicians. Understanding physicians’ experiences and factors influencing their decisions can lead to improvement in end-of ...
Nattanit Ketchaikosol, Kanokporn Pinyopornpanish, Chaisiri Angkurawaranon, Nisachol Dejkriengkraikul, Lalita Chutarattanakul   +4 more
doaj   +1 more source

Grain Filling and Some Fatty Acids Composition of Canola (Brassica napus L.) with Application of Bio-Fertilizers and Irrigation withholding [PDF]

Journal of Agricultural Science and Sustainable Production, 2017
The effect of irrigation withholding and bio-fertilizers on grain filling components, chlorophyll content and some fatty acids composition Gacomo cultivar of canola, was studied by  factorial experiment based on randomized complete block design with ...
Hossein Vatan Doost, R Seyed Sharifi, S Farzaneh, D Hassan Panah   +3 more
doaj