Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease [PDF]
This is an open-access article distributed under the terms of the Creative Commons Attribution License.Despite evidence about the implication of the bone marrow (BM) stromal microenvironment in multiple myeloma (MM) cell growth and survival, little is ...
Blanco, Juan F. +10 more
core +1 more source
Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids [PDF]
Evolution of the animal body plan is driven by changes in developmental gene regulatory networks (GRNs), but how networks change to control novel developmental phenotypes remains, in most cases, unresolved. Here, we address GRN evolution by comparing the
Davidson, Eric H. +2 more
core +1 more source
An observational cohort feasibility study to identify microvesicle and miRNA biomarkers of acute kidney injury following paediatric cardiac surgery [PDF]
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Objectives: Micro-RNA, small noncoding RNA fragments involved in gene regulation, and microvesicles ...
JnTala, Maria +9 more
core +1 more source
Wnt proteins regulate acetylcholine receptor clustering in muscle cells
Background The neuromuscular junction (NMJ) is a cholinergic synapse that rapidly conveys signals from motoneurons to muscle cells and exhibits a high degree of subcellular specialization characteristic of chemical synapses.
Zhang Bin +5 more
doaj +1 more source
Aim of the study : Examination of copy number changes in a group of intracranial germ cell tumors (GCTs) with particular focus on putative aberrations of the main genes coding SHh pathway proteins.
Dominika Kuleszo +7 more
doaj +1 more source
As a cardinal marker of brain ageing, lifetime brain atrophy obtained from a cross-sectional magnetic resonance image promises to boost statistical power to uncover novel genetic mechanisms of neurodegeneration.
Anna E. Fürtjes +23 more
doaj +1 more source
A gene regulatory network controlling the embryonic specification of endoderm [PDF]
Specification of endoderm is the prerequisite for gut formation in the embryogenesis of bilaterian organisms. Modern lineage labelling studies have shown that in the sea urchin embryo model system, descendants of the veg1 and veg2 cell lineages produce ...
Davidson, Eric H., Peter, Isabelle S.
core
DNA methylation status of the cell proliferation genes in atherosclerosis
The purpose of this study was to identify the features of methylation status of genes whose products are involved in the cell proliferation in vascular tissues of patients with atherosclerosis.
M. S. Nazarenko +7 more
doaj
SDR42E1 modulates vitamin D absorption and cancer pathogenesis: insights from an in vitro model
IntroductionVitamin D is a pleiotropic hormone essential for bone health and overall physiological function. Despite its significance, vitamin D deficiency remains widespread and is often influenced by genetic factors.
Nagham Nafiz Hendi +3 more
doaj +1 more source
UEG Week 2025 Moderated Posters
United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley +1 more source

