Results 61 to 70 of about 4,011 (186)

Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism. [PDF]

, 2019
Coordinated efforts between macrophages and epithelia are considered essential for wound healing, but the macrophage-derived molecules responsible for repair are poorly defined.
Beers, Michael F, Cohen, Noam A, Herbert, De'Broski R, Hung, Li-Yin, Katzen, Jeremey, Krummel, Matthew F, Nieves, Wildaliz, Oniskey, Taylor K, Sen, Debasish, Urisman, Anatoly, Vaughan, Andrew E   +10 more
core   +1 more source

An integrative bioinformatic approach for identifying subtypes and subtype-specific drivers in cancer [PDF]

, 2012
Cancer is a complex disease and within a cancer, subtypes of patients with distinct behaviors often exist. The subtypes might have been caused by different hits, such as copy number aberrations (CNAs) and point mutations, on different pathways/cells-of ...
Chen, P, Fan, Y, Hung, YS, Wong, STC
core   +1 more source

The Role of Wnt Signaling in Age‐Related Alveolar Bone Loss and Regeneration

Journal of Periodontal Research, EarlyView.
The graphical abstract summarizes key signaling pathways involved in bone formation and resorption associated with Wnt signaling across young and aged long bone and jaw tissues. Levels of evidence are indicated as robust, moderate, or emerging, reflecting the current experimental support in each context.
Hsiao H. Sung, Navya Chalamalasetty, Ali Alzainal, Hanlong Liu, Lexuan Wang, Pietra Colacrai Arikita, Ivy C. X. Wei, Hom‐Lay Wang, M. H. J. van den Bosch, Michelle S. Caird, Peter M. van der Kraan, Kenneth M. Kozloff, Esmeralda Blaney Davidson   +12 more
wiley   +1 more source

Identification of several potential chromatin binding sites of HOXB7 and its downstream target genes in breast cancer [PDF]

, 2015
Peer ...
Gao, Ping, Hautaniemi, Sampsa, Heinonen, Henna, Jänne, Olli A., Lepikhova, Tatiana, Louhimo, Riku, Monni, Outi Maria, Pehkonen, Henna Maria, Pihlajamaa, Päivi, Sahu, Biswajyoti, Wei, Gong-Hong   +10 more
core   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities. [PDF]

PLoS ONE, 2013
Functional and mechanistic studies of Wnt signaling have been severely hindered by the inaccessibility of bioactive proteins. To overcome this long-standing barrier, we engineered and characterized a panel of Chinese hamster ovary (CHO) cell lines with ...
Jennifer L Green, Matthieu Bauer, Kyu Won Yum, Yao-Cheng Li, Miranda L Cox, Karl Willert, Geoffrey M Wahl   +6 more
doaj   +1 more source

Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3. [PDF]

, 2011
RATIONALE: Recent work in animal models and humans has demonstrated the presence of organ-specific progenitor cells required for the regenerative capacity of the adult heart.
Bauer, Michael, Bayomy, Ahmad F, Biechele, Travis L, Conyers, Frank, Crapps, Dylan, Dong, Hanhua, Fine, Gabriel C, Force, Thomas, Guan, Jian, Han, Jung-Kyu, Liao, Annette, Liao, Ronglih, Moon, Randall T, Oikonomopoulos, Angelos, Sereti, Konstantina-Ioanna, Westerman, Karen   +15 more
core   +2 more sources

Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell‐of‐origin model for osteoid osteoma and osteoblastoma

The Journal of Pathology, Volume 268, Issue 3, Page 263-275, March 2026.
Abstract Osteoid osteoma and osteoblastoma are non‐malignant bone‐forming tumours of the skeleton, characterised by the presence of irregular trabeculae of woven bone. Rearrangements in FOS, and less frequently FOSB, have recently been identified in osteoid osteoma and osteoblastoma.
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy van den Akker, David GP van IJzendoorn, Harald MM Mikkers, Hailiang Mei, Anne‐Marie Cleton‐Jansen, Marieke L Kuijjer, Karoly Szuhai, Judith VMG Bovée   +10 more
wiley   +1 more source

Chemotherapeutical effects on Wnt16 secretion in human gliomas

, 2014
65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Dreher, L, Goldbrunner, R, Timmer, M
openaire   +1 more source

On the association between Chiari malformation type 1, bone mineral density and bone related genes

Bone Reports, 2022
Background: Chiari malformation type 1 (C1M) is a neurological disease characterized by herniation of the cerebellar tonsils below the foramen magnum. Cranial bone constriction is suspected to be its main cause. To date, genes related to bone development
Núria Martínez-Gil, Leonardo Mellibovsky, Demián Manzano-López González, Juan David Patiño, Monica Cozar, Raquel Rabionet, Daniel Grinberg, Susanna Balcells   +7 more
doaj   +1 more source