Results 81 to 90 of about 4,011 (186)

Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence [PDF]

open access: yes, 2016
Additional file 3: Figure S3. Regulation of genes of Arrhythmogenic right ventricular cardiomyopathy pathway during senescence induction in HFF strains Genes of the “Arrhythmogenic right ventricular cardiomyopathy” pathway which are significantly up ...
A Chicas   +215 more
core   +5 more sources

Pigments, Chromatophore Structure, and Gene Expression Underlying Colour Polytypy of a Panamanian Poison Frog

open access: yesMolecular Ecology, Volume 35, Issue 1, January 2026.
ABSTRACT Colour polytypism represents an example of phenotypic diversification shaped by genetic divergence and ecological pressures. Poison frogs of the genus Oophaga (Dendrobatidae) are highly polytypic in coloration, making them an ideal system for investigating the genetic and physiological basis of colour variation.
Vasiliki Mantzana‐Oikonomaki   +7 more
wiley   +1 more source

Large-scale association study for structural soundness and leg locomotion traits in the pig

open access: yesGenetics Selection Evolution, 2009
Background Identification and culling of replacement gilts with poor skeletal conformation and feet and leg (FL) unsoundness is an approach used to reduce sow culling and mortality rates in breeding stock.
Serenius Timo   +5 more
doaj   +1 more source

Emerging Roles of Wnt Ligands in Human Colorectal Cancer

open access: yesFrontiers in Oncology, 2020
Colorectal cancer (CRC) is the fourth leading cause of cancer death worldwide, and constitutive activation of the Wnt signaling pathway is universal in most CRC cases.
Xiaobo Nie   +5 more
doaj   +1 more source

Methylation status of Wnt signaling pathway genes affects the clinical outcome of Philadelphia-positive acute lymphoblastic leukemia [PDF]

open access: yes, 2008
The clinical significance of aberrant promoter methylation of the canonical Wnt pathway antagonist genes (sFRP1, sFRP2, sFRP4, sFRP5, Wif1, Dkk3, and Hdpr1) and also putative tumor-suppressor gene Wnt5a, belonging to the non-canonical Wnt signaling ...
Agirre-Ena, X. (Xabier)   +11 more
core   +1 more source

Association of Forced Vital Capacity with the Developmental Gene NCOR2.

open access: yesPLoS ONE, 2016
BackgroundForced Vital Capacity (FVC) is an important predictor of all-cause mortality in the absence of chronic respiratory conditions. Epidemiological evidence highlights the role of early life factors on adult FVC, pointing to environmental exposures ...
Cosetta Minelli   +21 more
doaj   +1 more source

The regulation of differentiation in mesenchymal stem cells [PDF]

open access: yes, 2010
Peer reviewedPublisher ...
Augello, Andrea, De Bari, Cosimo
core   +1 more source

Four Pharmacogenomic Variants Strongly Linked to Corticosteroid‐Induced Avascular Necrosis in Children with Cancer

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1844-1854, December 2025.
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado   +9 more
wiley   +1 more source

WNT16 induces proliferation and osteogenic differentiation of human perivascular stem cells

open access: yesJournal of Orthopaedics, 2018
Perivascular stem cells (PSC) are a progenitor population defined by their perivascular residence. Recent studies have examined the relative difference in Wnt ligands to induce PSC differentiation, including Wnt16. Here, we examine the role of Wnt16 in the proliferation and osteogenic differentiation of human PSC.
Carolyn A, Meyers   +3 more
openaire   +3 more sources

Genome-wide association study of serum iron phenotypes in premenopausal women of European descent [PDF]

open access: yes, 2016
A genome-wide association study was performed in 1,130 premenopausal women to detect common variants associated with three serum iron-related phenotypes. Total iron binding capacity was strongly associated (p=10−14) with variants in and near the TF gene (
Acton, Dena   +8 more
core   +1 more source

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