Results 131 to 140 of about 289,302 (355)

Wnt signal transduction pathway and apoptosis: a review

Cancer Cell International, 2010
The association between the wnt signaling pathway and apoptosis has become more firmly established in the recent scientific literature. Many reports indicate that the wnt signaling pathway regulates apoptosis through a variety of mechanisms. The activity
Pećina-Šlaus Nives
doaj   +1 more source

Additional file 3 of A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial–mesenchymal transition via the canonical Wnt/β-catenin signaling pathway

, 2021
Xuxi Chen, Wuyang Yue, Lin Tian, Na Li, Yiyi Chen, Lishi Zhang, Jinyao Chen   +6 more
openalex   +1 more source

Retraction Note: TRIM29 facilitates the epithelial‑to-mesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/β-catenin signaling pathway [PDF]

, 2022
Juntao Sun, Tianyu Zhang, Mengmeng Cheng, Liwen Hong, Chen Zhang, Mengfan Xie, Peijun Sun, Rong Fan, Zhengting Wang, Lei Wang, Jie Zhong   +10 more
openalex   +1 more source

Wnt Signalling Pathway Parameters for Mammalian Cells

PLoS ONE, 2012
Wnt/β-catenin signalling regulates cell fate, survival, proliferation and differentiation at many stages of mammalian development and pathology. Mutations of two key proteins in the pathway, APC and β-catenin, have been implicated in a range of cancers, including colorectal cancer. Activation of Wnt signalling has been associated with the stabilization
Tan, C.W., Gardiner, B.S., Hirokawa, Y., Layton, M.J., Smith, D.W., Burgess, A.W.   +5 more
openaire   +5 more sources

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Integrin Activation Contributes to Lower Cisplatin Sensitivity in MV3 Melanoma Cells by Inducing the Wnt Signalling Pathway [PDF]

, 2017
Roberta Piva, Bastian Jakubzig, Gerd Bendas   +2 more
openalex   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study

, 2015
The last decade has seen an explosion in models that describe phenomena in systems medicine. Such models are especially useful for studying signaling pathways, such as the Wnt pathway.
A Gelman, A Saltelli, AC Babtie, AG Fletcher, AL MacLean, AL MacLean, AR Hernández, B Alberts, B Carlin, B Lloyd-Lewis, BR Henderson, CW Gardiner, CW Tan, CW Tan, CY Logan, D Brewer, D Cox, D Kim, E Feliu, E Lee, ER Barry, F Cong, G Craciun, G Craciun, G Craciun, GR Mirams, H Clevers, H Kitano, HA Harrington, I Ramis-Conde, IMM Leeuwen van, J Franca-Koh, J Heuberger, J Jost, J Liepe, J Liepe, J Neumann von, J Stark, J Stelling, J. Kevorkian, K Itoh, KH Cho, L Goentoro, L Vermeulen, M Basan, M Beguerisse-Díaz, M Feinberg, M Feinberg, M Kuhl, M Secrier, M Sunnåker, N Blüthgen, N Gershenfeld, N Gilbert, N Wiechens, O Ratmann, P Buske, P Glendinning, P Kirk, P Polakis, PJ Murray, PJ Murray, R Habas, R Krüger, RN Gutenkunst, S Wolfram, T Reya, T Toni, VSW Li, X Varelas, Y Kogan, Y Schmitz, Y Schmitz, Y Zhou   +73 more
core   +1 more source

The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape.

Trends in genetics : TIG, 2000
Members of the vertebrate Wnt family have been subdivided into two functional classes according to their biological activities. Some Wnts signal through the canonical Wnt-1/wingless pathway by stabilizing cytoplasmic beta-catenin. By contrast other Wnts stimulate intracellular Ca2+ release and activate two kinases, CamKII and PKC, in a G-protein ...
Kuhl, M., Sheldahl, L. C., Park, M., Miller, J. R., Moon, R. T.   +4 more
openaire   +2 more sources