Results 161 to 170 of about 270,248 (329)

Low-Density Lipoprotein Receptor-Related Protein-5 Binds to Axin and Regulates the Canonical Wnt Signaling Pathway [PDF]

, 2001
Junhao Mao, Jiyong Wang, Bo Liu, Weijun Pan, Gist H. Farr, Christopher Flynn, Huidong Yuan, Shinji Takada, David Kimelman, Li Lin, Dianqing Wu   +10 more
openalex   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Wnt signaling pathways in biology and disease: mechanisms and therapeutic advances

Signal Transduction and Targeted Therapy
The Wnt signaling pathway is critically involved in orchestrating cellular functions such as proliferation, migration, survival, and cell fate determination during development.
Chen Xue, Qingfei Chu, Qingmiao Shi, Yifan Zeng, Juan Lu, Lanjuan Li   +5 more
doaj   +1 more source

Akt Participation in the Wnt Signaling Pathway through Dishevelled [PDF]

, 2001
Shinya Fukumoto, Chung-Ming Hsieh, Koji Maemura, Matthew D. Layne, Shaw‐Fang Yet, Kyung-Han Lee, Takashi Matsui, Anthony Rosenzweig, William G. Taylor, Jeffrey S. Rubin, Mark A. Perrella, Mu-En Lee   +11 more
openalex   +1 more source

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

Advanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu, Rockie Haiyao Ding, Zixuan Zhao, Clara Yieh Lin Chong, Ruochii You, Hengjia Zhou, Dong Hua Seah, Wei Qiang Leow, Hong Kit Lim, Sukanya Shyamasundar, Kanishka Fernando, Fathima Farzana Kuthubudeen, Gillian Ng, Chor Yong Tay, Narayanan Gopalakrishna Iyer, Chin‐Ann Johnny Ong, Eliza Li Shan Fong   +16 more
wiley   +1 more source

Synergistic Activation of the Wnt Signaling Pathway by Dvl and Casein Kinase Iε [PDF]

, 2001
Michiko Kishida, Shin‐ichiro Hino, Tatsuo Michiue, Hideki Yamamoto, Shosei Kishida, Akimasa Fukui, Makoto Asashima, Akira Kikuchi   +7 more
openalex   +1 more source

Vascularized and Perfusable Human Heart‐on‐a‐Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery

Advanced Materials, EarlyView.
This novel 3D human ischemic heart‐on‐a‐chip, with perfusable vasculature directly interfaced with myocardial tissue, replicates key aspects of ischemic heart injury. It also demonstrates the targeted delivery and therapeutic efficacy of cardiac homing peptide‐conjugated liposomes, validating the platform for drug and nanomedicine screening in ...
Junyoung Kim, Xuening Zhang, Richard Wang, Adrian Najer, Qiao You Lau, Ana Cammack‐Najera, Jang Ah Kim, Yoo Kyung Kang, Ruoxiao Xie, Hyemin Kim, Kai Xie, Hyeonji Lim, Tae‐Eun Park, Jinmyoung Joo, Molly M. Stevens   +14 more
wiley   +1 more source

Hepatic Adenomas: Analysis of Sex Steroid Receptor Status and the Wnt Signaling Pathway [PDF]

, 2002
Michael Torbenson, Jae-Hyuk Lee, Michael A. Choti, Wesley R. Gage, Susan C. Abraham, Elizabeth Montgomery, John Boitnott, Tsung‐Teh Wu   +7 more
openalex   +1 more source

Filamented Light (FLight) Bioprinting of Mini‐Muscles with Self‐Renewal Potential

Advanced Materials, EarlyView.
This work presents the FLight biofabrication for engineering in vitro muscle constructs by photocrosslinking pristine collagen and fibrinogen using ruthenium. The resulting mini‐muscles retain in vivo‐like tissue organization and a Pax7⁺ cell pool.
Hao Liu, Michael Winkelbauer, Jakub Janiak, Patrick Weber, Ali Kerem Kalkan, Inseon Kim, Parth Chansoria, Ori Bar‐Nur, Marcy Zenobi‐Wong   +8 more
wiley   +1 more source

Designing the Next Generation of Biomaterials through Nanoengineering

Advanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr., Ishaan Duggal, Nicholas A. Peppas, Akhilesh K. Gaharwar   +3 more
wiley   +1 more source