Results 221 to 230 of about 270,248 (329)

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Modified Huanjingjian Prevents Chemotherapy-Induced Alopecia by Inhibiting Genomic DNA Methylation of the Wnt Signaling Pathway in Mice. [PDF]

Drug Des Devel Ther
Liu X, Du T, Xi R, Cheng L, Wang Y, Lu H, Guo D, Zhu J, Liu T, Li F.   +9 more
europepmc   +1 more source

Tcl-2 encodes a novel protein that acts synergistically with Wnt signaling pathways in C. elegans

, 2003
Xiaojun Zhao, Hitoshi Sawa, M.A. Herman
openalex   +1 more source

mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: Identification of IL-20 receptor-mediated bystander activity against pancreatic cancer [PDF]

, 2005
Sunil Chada, Dora Bocangel, Rajagopal Ramesh, Elizabeth A. Grimm, John B. Mumm, Abner M. Mhashilkar, Mingzhong Zheng   +6 more
openalex   +1 more source

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut‐Liver‐on‐a‐Chip Models

Advanced Science, EarlyView.
The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye, Shi Li, Guofang Bi, Binghui Li, Zhai Cai, Meixian Jin, Ying Zhang, Wanren Yang, Yang Li, Shao Li, Wei Hu, Yi Gao, Mingxin Pan, Shuqin Zhou, Chao Zhang, Huichang Bi, Qing Peng   +16 more
wiley   +1 more source

MEIS1 knockdown upregulates WNT signaling pathway genes in esophageal squamous cell carcinoma. [PDF]

BMC Med Genomics
Hosseini N, Forghanifard MM.
europepmc   +1 more source

Metformin: A New Inhibitor of the Wnt Signaling Pathway in Cancer. [PDF]

Cells, 2023
Conza D, Mirra P, Fiory F, Insabato L, Nicolò A, Beguinot F, Ulianich L.   +6 more
europepmc   +1 more source

Down‐regulation of Dickkopf 3, a regulator of the Wnt signalling pathway, in elderly schizophrenic subjects [PDF]

, 2005
Saoussen Ftouh, Mohammed T. Akbar, Steven R. Hirsch, Jacqueline de Belleroche   +3 more
openalex   +1 more source

Single‐Cell RNA Sequencing Reveals the Heterogeneity in Differentiation Trajectory and Tumor Microenvironment Leading to More Aggressive Phenotypes of Papillary Thyroid Cancer in Children and Young Adult Patients

Advanced Science, EarlyView.
scRNA sequencing reveals distinct tumor ecosystem features in CAYA‐PTC, marked by enriched CD4T_Tfh, CD8T_Tex cells, and rapid malignant thyrocyte differentiation (absent of mild‐state BRAF‐like population) toward invasive states. Prominent emCAF_LAMP5 populations interact with endothelial cells and thyrocytes facilitate angiogenesis and metastasis ...
Kai Guo, Lingyi Yang, Zirui Huang, Kai Qian, Yuan Shi, Mengjia Fei, Yuan Feng, Zixian Chen, Ming Qiu, Linglin Tang, Anqi Li, Zhibao Lv, Jiangbin Liu, Zhou Chen, Kuiran Dong, Zhuoying Wang   +15 more
wiley   +1 more source

Endometrial stromal Menin supports endometrial receptivity by maintaining homeostasis of WNT signaling pathway through H3K4me3 during WOI. [PDF]

Commun Biol
Xu X, Han Y, Jin K, Xu W, Zhang H, Ma Y, Li X, Wang H, Liu M, Lin X.   +9 more
europepmc   +1 more source