Results 221 to 230 of about 289,302 (355)

Response to Wnt Signaling Pathways

Journal of Bone and Mineral Research, 2015
Merry Jo Oursler, Jennifer J Westendorf, Megan M Weivoda, Ming Ruan, Christine M Hachfeld, Alan Howe, Rachel Davey, Jeffrey Zajac, Bart O Williams, Sundeep Khosla   +9 more
openaire   +1 more source

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

Advanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang, Ziwen Gao, Hui Huang, Chanyuan Zhang, Yiquan Tang, Qianhui Qu, Huabin Li, Jing Ke, Zhiji Chen, Menglong Feng, Hu Zhou, Yilai Shu, Wei Yuan   +12 more
wiley   +1 more source

ZIC5, a survival biomarker, facilitates tumor progression and stemness in colon cancer via the activation of the Wnt signaling pathway. [PDF]

Sci Rep
Li X, Zhao C, Mu M, Yuan H, Chen G, Chen S, Huo X, Sun X, Yu J.   +8 more
europepmc   +1 more source

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

Advanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim, Hanjun Hwangbo, ByungJoon Choi, Dogeon Yoon, GeunHyung Kim   +4 more
wiley   +1 more source

LILRB4 regulates circadian disruption-induced mammary tumorigenesis via non-canonical WNT signaling pathway. [PDF]

Oncogene
Ogunlusi O, Sarkar M, Carter K, Chakrabarti A, Boland DJ, Nguyen T, Sampson J, Nguyen C, Fails D, Jones-Hall Y, Fu L, Wright G, Kim DM, Cai JJ, Mallick B, Keene AC, Jones JR, Roy Sarkar T.   +17 more
europepmc   +1 more source

Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/β-catenin signaling pathway

, 2017
Tiantian Wang, Mei Wang, Shuang Fang, Qiang Wang, Rui Fang, Jie Chen   +5 more
openalex   +2 more sources

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

Advanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si   +10 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

CRP and HNF1A collaborate to regulate the progression of laryngeal cancer through the Wnt signaling pathway. [PDF]

Funct Integr Genomics
Zhao Z, Zhu X, Xu J, Song P, Sun Y, Yang Z, Wang L, Zhang J, Zhao R, Chen X, Li W, Tian L, Liu M.   +12 more
europepmc   +1 more source

Inhibition of the Wnt/β‑catenin signaling pathway reduces autophagy levels in complement treated podocytes

, 2021
Zhaocheng Dong, Haoran Dai, Yu Gao, Zhendong Feng, Wenbin Liu, Fei Liu, Zihan Zhang, Fang Ma, Xinran Xie, Zebing Zhu, Weijing Liu, Baoli Liu   +11 more
openalex   +2 more sources