Results 81 to 90 of about 115 (110)
Investigating the Roles of Wntless (Wls) Isoforms in Wingless (Wg) Signaling
The FASEB Journal, 2013 Wnts are secreted signaling molecules that have essential functions in development and adult homeostasis. Wnt family proteins and their signaling pathway are conserved from humans to invertebrates. Wingless (Wg) is the founding Drosophila Wnt family member. In the wing disc, secreted Wg forms
Nicholas J Lombardi, Erica Selva
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Low expression of D2R and Wntless correlates with high motivation for heroin.
Behavioral Neuroscience, 2015 Drug overdose now exceeds car accidents as the leading cause of accidental death in the United States. Of those drug overdoses, a large percentage of the deaths are due to heroin and/or pharmaceutical overdose, specifically misuse of prescription opioid analgesics.
Diana M, Tacelosky +6 more
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Wnt5a Promotes Axon Elongation in Coordination with the Wnt–Planar Cell Polarity Pathway
CellsThe establishment of neuronal polarity, involving axon specification and outgrowth, is critical to achieve the proper morphology of neurons, which is important for neuronal connectivity and cognitive functions.
Samar Ahmad, Liliana Attisano
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Direct visualization of the Wntless-induced redistribution of WNT1 in developing chick embryos
Developmental Biology, 2018 Paracrine Wnt signals are critical regulators of cell proliferation, specification, and differentiation during embryogenesis. Consistent with the discovery that Wnt ligands are post-translationally modified with palmitoleate (a 16 carbon mono-unsaturated fatty acid), our studies show that the vast majority of bioavailable chick WNT1 (cWNT1) produced in
Lisa M. Galli +5 more
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Hepatology Communications, 2018 β‐Catenin in hepatocytes, under the control of Wnts, regulates pericentral gene expression. It also contributes to liver regeneration (LR) after partial hepatectomy (PH) by regulating cyclin‐D1 gene expression as shown in the β‐catenin and Wnt ...
Morgan Preziosi +4 more
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Spatial gene expression profile of Wnt-signaling components in the murine enteric nervous system
Frontiers in ImmunologyIntroductionWnt-signaling is a key regulator of stem cell homeostasis, extensively studied in the intestinal crypt and other metazoan tissues. Yet, there is hardly any data available on the presence of Wnt-signaling components in the adult enteric ...
Melanie Scharr +2 more
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PLoS ONEPrimordial follicle activation (PFA) is a pivotal event in female reproductive biology, coordinating the transition from quiescent to growing follicles.
Hinako M Takase +6 more
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American journal of clinical and experimental urology, 2022 Resistance to androgen receptor (AR) targeted therapies remains as the main reason for most prostate cancer related deaths. Lineage plasticity resulting in altered, treatment insensitive prostate tumor cell phenotypes such neuroendocrine differentiated prostate cancer is a common manifestation within resistant tumors upon AR-targeted therapies.
D'Abronzo, Leandro S +8 more
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Stem Cell Research & TherapyBackground The use of mesenchymal stem cells (MSCs) is recognized as a promising strategy for the treatment of androgenetic alopecia (AGA). However, the underlying mechanism remains to be explored. Here, we evaluated the therapeutic effects and potential
Wenjing Yan +10 more
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