Results 51 to 60 of about 4,811,493 (268)

A scoping review of person-centred maternity care service in humanitarian and fragile settings

BMJ Global Health
Introduction Women who live in humanitarian settings are three times more likely to die than those who live in peaceful environments. Person-centred maternity care (PCMC) is a fundamental human right for every woman, yet it is often overlooked in ...
Robera Olana Fite, Wubshet D Negash, Kamalini Lokuge   +2 more
doaj   +1 more source

Continuity of care, continuity of service

International Journal of Cardiology Congenital Heart Disease, 2020
Heart disease is the single major cause of maternal mortality in developed countries. 0.8% of babies are born with a congenital heart defect and because most now survive to adulthood, providing care for mothers with a congenital heart defect makes up the
Philip J. Steer
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Woman-centred care and integrated electronic medical records within Australian maternity settings: Point prevalence audit and observational study

, 2023
Woman-centred care and integrated electronic medical records within Australian maternity settings: Point prevalence audit and observational ...
A Craswell (9851387), M Hadland (16036115), L Kearney (14595740), R Cole (7747736), W Smyth (13325928), Catherine Nagle (13063122)   +5 more
core   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Accounting for Research – the Difficulties Posed for User-Centred Research [PDF]

, 2006
When public money is invested in research it is necessary to have in place accounting systems that demonstrate its value. By this we mean its social as much as its economic value to society.
Minogue, Virginia, Grant, Gordon, Walsh, Mike, Courtney, Duncan, King, Sarah, Shields, Graham, Walsh, Michael   +6 more
core   +2 more sources

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

The first Global Conference on Person-Centred Care : knowledge(s) and innovations for health in changing societies : abstract book [PDF]

This is the abstract book for the first Global Conference on Person-Centred Care (GCPCC), taking place in Gothenburg, Sweden, from 13th–16th May, 2024.
Global Conference on Person-Centred Care 1 2024 Göteborg
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