Results 51 to 60 of about 2,815,176 (310)

Challenging gender myths: Promoting inclusive wheat and maize research for development in Nepal [PDF]

open access: yes, 2020
This technical note provides research evidence debunking four gender myths: 1) men are the main decision makers; 2) women don’t do much in wheat and maize; 3) women don’t innovate; and 4) women lack resources for innovation.
Badstue, Lone B.   +4 more
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Home Bound Working Women and Organizational Efficiency of Developing Economy

open access: yesInternational Journal of Experiential Learning & Case Studies, 2017
This research aims to understand the preferences of educated unemployed women of Pakistan and India on the imposition of the law of “Flex time/rules for home bound educated women”.
Babar Ansari   +2 more
doaj   +3 more sources

Thyroid cancer among female workers in Korea, 2007–2015

open access: yesAnnals of Occupational and Environmental Medicine, 2018
Background Prevalence of thyroid cancer has been increasing rapidly worldwide, especially among women. There has been a debate as to whether such an increase represents consequences of over-diagnosis or a true increase.
Seonghoon Kang   +5 more
doaj   +1 more source

Labour Force Participation of Women Over 45 [PDF]

open access: yes
This Productivity Commission staff working paper (by Geoff Gilfillan and Les Andrews) was released in January 2011. The contribution of mature aged women (aged 45 to 64 years) to total hours worked in the economy by people of working age has increased ...
G, Gilfillan, L, Andrews
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

A qualitative study of factors affecting mental health amongst low-income working mothers in Bangalore, India. [PDF]

open access: yes, 2014
BackgroundLow-income urban working mothers face many challenges in their domestic, environmental, and working conditions that may affect their mental health.
Heymann, Sally Jody   +2 more
core   +3 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy