Results 51 to 60 of about 12,765,785 (291)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Strategies to minimize false positives and interpret novel microdeletions based on maternal copy-number variants in 87,000 noninvasive prenatal screens

BMC Medical Genomics, 2018
Background Noninvasive prenatal screening (NIPS) of common aneuploidies using cell-free DNA from maternal plasma is part of routine prenatal care and is widely used in both high-risk and low-risk patient populations.
Kristjan Eerik Kaseniit, Gregory J Hogan, Kevin M D’Auria, Carrie Haverty, Dale Muzzey   +4 more
doaj   +1 more source

Investigation of Women’s Health on Wikipedia—A Temporal Analysis of Women’s Health Topic

Informatics, 2020
New health-related concepts, terms, and topics emerge, and the meanings of existing terms and topics keep changing. This study investigated and explored the evolutions of the women’s health topic on Wikipedia.
Yanyan Wang, Jin Zhang
doaj   +1 more source

Additional file 6: Table S4. of Anthropometric measures and serum estrogen metabolism in postmenopausal women: the Womenâ s Health Initiative Observational Study

, 2017
Geometric means (pmol/L) and 95% CIs of serum estrogens/estrogen metabolites by current BMI in postmenopausal women not using menopausal hormone therapy among control subjects only in the Womenâ s Health Initiative Observational Study. (PDF 103 kb)
Oh, Hannah, Coburn, Sally, Matthews, Charles, Falk, Roni, LeBlanc, Erin, Wactawski-Wende, Jean, Sampson, Joshua, Pfeiffer, Ruth, Brinton, Louise, Wentzensen, Nicolas, Anderson, Garnet, Manson, JoAnn, Chen, Chu, Zaslavsky, Oleg, Xu, Xia, Trabert, Britton   +15 more
openaire   +1 more source

Women and non communicable diseases (chronic conditions) [PDF]

, 2014
Non-communicable diseases (cancer, cardiovascular disease, diabetes, chronic respiratory conditions, and musculo-skeletal conditions) are the number one cause of death and disablement for women and men globally and in Australia, with increasing ...

core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Iron status and anemia in a population-based study of women with and without disability living in the community: the Women's Health and Aging Studies

Haematologica, 2004
Iron status and associated risk factors were assessed in a population-based study of 684 community-dwelling women, 70-79 years old. Iron deficiency, iron deficiency anemia, and elevated iron stores were found in 5.8%, 3.8%, and 9.0% of women ...
RD Semba, JM Guralnik, P Chaves, MO Ricks, LP Fried, Women's Health and Aging Studies   +5 more
doaj  

Additional file 4: Table S2. of Anthropometric measures and serum estrogen metabolism in postmenopausal women: the Womenâ s Health Initiative Observational Study

, 2017
Geometric means (pmol/L) and 95% CIs of serum estrogens/estrogen metabolites by waist-to-hip ratio in postmenopausal women currently using menopausal hormone therapy in the Womenâ s Health Initiative Observational Study. (PDF 95 kb)
Oh, Hannah, Coburn, Sally, Matthews, Charles, Falk, Roni, LeBlanc, Erin, Wactawski-Wende, Jean, Sampson, Joshua, Pfeiffer, Ruth, Brinton, Louise, Wentzensen, Nicolas, Anderson, Garnet, Manson, JoAnn, Chen, Chu, Zaslavsky, Oleg, Xu, Xia, Trabert, Britton   +15 more
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Additional file 5: Table S3. of Anthropometric measures and serum estrogen metabolism in postmenopausal women: the Womenâ s Health Initiative Observational Study

, 2017
Geometric means (pmol/L) and 95% CIs of serum estrogens/estrogen metabolites by BMI at age 18 years in postmenopausal women in the Womenâ s Health Initiative Observational Study. (PDF 94 kb)
Oh, Hannah, Coburn, Sally, Matthews, Charles, Falk, Roni, LeBlanc, Erin, Wactawski-Wende, Jean, Sampson, Joshua, Pfeiffer, Ruth, Brinton, Louise, Wentzensen, Nicolas, Anderson, Garnet, Manson, JoAnn, Chen, Chu, Zaslavsky, Oleg, Xu, Xia, Trabert, Britton   +15 more
openaire   +1 more source