Results 121 to 130 of about 262,700 (294)
Advanced Science, EarlyView.THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
Acta AmazonicaBrazil stands out as one of the largest manufacturers of MDF (medium density fiberboard) in the world. The industries are concentrated in the south and southeast of the country and are primarily based on the use of Pinus and Eucalyptus wood, which are ...
Victor Cezar Nepomuceno RIBEIRO +1 more
doaj +1 more source
Advanced Science, EarlyView.Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang +12 more
wiley +1 more source
Advanced Science, EarlyView.Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He +9 more
wiley +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
BioResourcesPhysical and mechanical properties were investigated for wood-based sandwich panels reinforced with basalt fiber fabric (BFF), glass fiber fabric (GFF), and jute fabric (JF).
Abdurrahman Karaman, Hikmet Yazıcı
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Preliminary Investigation of the Properties of Oriented Strand Boards Produced Using Green Adhesives
BuildingsIn this work, we sought to study the properties of OSB panels manufactured with new green adhesives for wood that can replace formaldehyde-based wood adhesives currently on the market.
Mario Núñez-Decap +5 more
doaj +1 more source
Urban Design of Bristol Waterfront, Lower Thames Street [PDF]
, 2013 The marketplace is going to be one of the highlights on Thames Street, serving as a destination for leisure, shopping and dining. The concept of the project is to have indoor space continue out to the water, providing an outdoor space for dining and ...
Bombara, Lauren +15 more
core +1 more source
Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China
Advanced Science, EarlyView.This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang +3 more
wiley +1 more source
EVALUATION OF THE EXPERIMENTAL PRODUCTION OF EUCALYPT CLEAR BLOCKS FOR GLUED WOOD PANELS
Floresta e AmbienteThe plywood panels and particleboards are examples of wood composites materials. Materials like MDF (“medium density fiberboard”), LVL (“laminated veneer lumber”) and the sidelong-glued panels constitute a new generation of wood based product.
Alexandre Monteiro de Carvalho +2 more
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